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      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  16 upvotes 2 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 5 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

      in Research/Science  251 upvotes 1 year ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community Kintor pyrilutamide presentation?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 6 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community Pyrilutamide kintor pharmaceutical

      in Chat  6 upvotes 2 years ago
      The conversation is about seeking information on GT20029 from Kintor Pharmaceutical as a potential hair loss cure and inquiring about experiences with CosmeaRNA.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  173 upvotes 6 months ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community Kintor long term safety phase 3

      in Research/Science  66 upvotes 1 year ago
      Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

      community Breezula Phase 3 confusion - did they change something?

      in Chat  10 upvotes 4 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

      community Disappointing news on Breezula/CB-03-01

       22 upvotes 7 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.

      community Why is there no feedback on pge2/setipiprant?

      in Question  5 upvotes 9 years ago
      The conversation questions the lack of feedback on the effectiveness of PGE2 and setipiprant for hair loss, despite their availability. The user is puzzled by the absence of reviews or results, whether positive or negative.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.