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      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 2 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community Castor Oil + Coconut Oil + Derma Rolling

      in Treatment  8 upvotes 8 years ago
      A user is experiencing temple hair recession and is seeking alternatives to finasteride. They are considering castor oil, coconut oil, and derma rolling, and have seen some improvement with Zenegen.

      community 5 months progress on fin and min

      in Progress Pictures  1838 upvotes 1 year ago
      Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

      community 5.5 month progress - 3500 grafts- WSC clinic Istanbul

      in Progress Pictures  14 upvotes 2 years ago
      A user underwent a hair transplant with 3500 grafts at WSC clinic in Istanbul and uses finasteride, biotin, multivitamins, minoxidil with finasteride, biotin shampoo, and coconut oil with peppermint oil for hair loss treatment. Another user commented that the result looks like a barren patch of hair.

      community Injecting estrogen for hairline regrow

      in Chat  267 upvotes 11 months ago
      A user plans to undergo a temporary MtF transformation to regrow hair, using estrogen, RU58841, and Dutasteride, then revert with testosterone. Many users criticize the plan, suggesting alternatives like hair transplants, and emphasize that estrogen is not a reliable solution for hair regrowth.

      community Oral minoxidil and lowering the dose?

      in Minoxidil  1 upvotes 1 year ago
      The user is experiencing significant hair regrowth with 5 mg oral minoxidil and 1 mg finasteride but also side effects like eye puffiness and hypertrichosis. They are considering reducing the minoxidil dose to 2.5 mg to lessen side effects and are curious about caffeine serums for eye puffiness.

      community My follicles are getting ready to throw in the towel 😮‍💨

      in Satire  443 upvotes 2 months ago
      The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, and RU58841, and debates the merits of being bald versus using hair systems. Opinions vary on confidence and attractiveness related to baldness and hair systems.

      community Latanoprost from the gray market?

      in Chat  4 upvotes 1 year ago
      The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.

      community Female Hair loss

      in Female  16 upvotes 6 years ago
      Women also experience hair loss, especially post-menopause, often requiring lifestyle changes. Treatments include Scalp Micropigmentation, hair transplants, and sometimes finasteride, with underlying causes needing medical evaluation.

      community Please do not get a Hair Transplant in Turkey

      in Transplants  859 upvotes 10 months ago
      Hair transplants in Turkey can be risky due to unqualified practitioners and high patient volumes, but some clinics offer good results if researched properly. It's crucial to choose a reputable clinic and doctor, as experiences vary widely.

      community New York Magazine article - the Great Unbalding

      in Research/Science  45 upvotes 7 months ago
      PP405, a potential treatment for male pattern baldness, shows promise with some participants experiencing hair regrowth in early trials. However, it is not yet considered a cure and may be used alongside existing treatments like minoxidil and finasteride.

      community CB-03-01 / Breezula Personal Results

      in Treatment  13 upvotes 2 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community Verterporfin combined with hairline lowering?

      in Technology  8 upvotes 2 years ago
      Verteporfin might be a potential cure for hair loss and could heal scars, which may lead to natural-looking results when combined with hairline lowering surgery. One person suggests waiting to see if verteporfin actually works as claimed.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 2 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 9 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Nizoral doesn't seem to be working. Rogaine not suggested by doctor due to cost and poor track record on females. Ideas?

      in Ketoconazole  23 upvotes 7 years ago
      A woman experiencing hair loss and facial hair growth suspects PCOS or androgenic alopecia and is considering treatments like Rogaine, but is concerned about the cost. She has tried various hair care methods and is awaiting a hormone doctor appointment, while others suggest she may have a hormonal imbalance and recommend seeing a gynecologist or trying cheaper versions of Rogaine.

      community Post Low-Level Laser Light Therapy Syndrome (PLLLTS )

      in Satire  5 upvotes 3 years ago
      Hair loss discussion includes LLLT treatments and a satirical condition called PLLLTS, causing patients to resemble lighthouses and attract moths. Some users express concern about others taking the satire seriously.

      community Follicum releases some data from previous phase 2a trial

      in Research/Science  13 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.