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      community 2years progress (21 years old)

      in Progress Pictures  107 upvotes 1 year ago
      A user shared their two-year progress using 1mg finasteride, topical minoxidil, and occasional microneedling, noting no significant changes but a halt in hair loss progression. They recently started oral minoxidil and are considering a hair transplant.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 6 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community RU58841 2.5% in Minoxidil 5% 3ml twice a day - Less Hairfall "BUT"

      in Treatment  2 upvotes 2 years ago
      The user mixed RU58841 with Minoxidil for hair loss treatment and experienced reduced hair fall and thicker hair but stopped due to chest pain and muscle twitching. They plan to use a new routine without RU58841 or Finasteride due to side effects, including various topical treatments and peptides.

      community Any other non-responders to most medications?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 2 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community 2 years update from 2021 to 2023.

      in Progress Pictures  76 upvotes 3 years ago
      LagRag revived their hair using finasteride, minoxidil, derma rolling, dermapen, and biotin shampoo. Users discussed the effectiveness and requested photos with different hair positions.

      community Should I start fin+min treatment? Norwood 2

      in Treatment  2 upvotes 3 years ago
      25-year-old male with Norwood 2 hair loss tried PRP injections without success. Dermatologists didn't recommend finasteride or minoxidil, but suggested PRP + Mesotherapy for 50% improvement.

      community Anyone know how to get second gen NSAA in the uk.

      in Transgender  1 upvotes 7 months ago
      A transwoman is struggling with hair loss despite using hormones, dutasteride, and Abiraterone, and is considering making her own treatments due to difficulty accessing them. She has also tried Eucapil and regularly uses Nizoral shampoo.

      community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

      in Chat  45 upvotes 3 months ago
      Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

      community Nandrolone Replacement Therapy

      in Treatment  43 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community 52 days since adding RU 25 mg nightly

      in Progress Pictures  17 upvotes 3 months ago
      The user added RU58841 to their finasteride and minoxidil routine, noticing significant improvement in hairline after 52 days. Some users warn about potential side effects of RU58841, while others express curiosity and congratulate the progress.

      community 11 month Progress 17-18yo with RU58841*

      in Progress Pictures  49 upvotes 1 year ago
      The user experienced hair regrowth using a combination of Minoxidil, Finasteride, and RU58841, with Minoxidil used initially and the other treatments added later. The user believes the combination of Finasteride and RU58841 contributed to the regrowth, with RU sourced from MVsupplement.

      community Allergan recruiting for Setipiprant trial in the US

       12 upvotes 8 years ago
      The conversation discusses a clinical trial for Setipiprant in the US, starting June 29th, with eligibility excluding recent users of minoxidil or finasteride. It encourages informed decision-making before signing up.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Do we have anything in the pipeline that is used as a replacement for minoxidil?

      in Minoxidil  17 upvotes 1 year ago
      The conversation discusses hair loss treatments, focusing on alternatives to Minoxidil, such as Bimatoprost and Latanoprost, and the use of Finasteride, Dutasteride, RU58841, and microneedling. The user plans to add Latanoprost to their regimen, which already includes oral and topical Minoxidil and Finasteride, Ketoconazole shampoo, and microneedling.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

      in Product  1 upvotes 3 weeks ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  12 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community RootBioTec? Basil extract for hair growth

      in Product  4 upvotes 1 year ago
      RootBioTec, a basil hairy root extract, claims to reduce hair loss by 31% in two months by inhibiting 5α reductase II and stimulating hair follicles. There is limited independent information available about its effectiveness.

      community the ordinary retinol & minoxidil

      in Minoxidil  13 upvotes 11 months ago
      Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

      community Topical bicalutamide vs ru58841

      in Female  1 upvotes 1 year ago
      A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.