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      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community How exactly is Eucapil (fluridil) approved in Europe?

      in Product  6 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil (fluridil) is approved as a cosmetic hair-care agent in Europe, but users question the level of testing required for approval.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Does Fluridil even work? (Eucapil)

      in Treatment  7 upvotes 4 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil's effectiveness is questioned due to unconvincing clinical trial and lack of FDA approval.

      community Microneedling + topical fin/min: how to structure the routine?

      in General  78 upvotes 6 months ago
      The user is using a topical spray containing finasteride, minoxidil, ketoconazole, and biotin for hair loss and plans to add weekly dermastamping, starting with a needle length of 0.6mm. They seek advice on the safety of combining these treatments, the impact of skipping one dose weekly, and the frequency of replacing the dermastamp.

      community Is adding RCP(redensyl, capixyl, procapil) over min+fin make sense?

      in Technology  5 upvotes 11 months ago
      The conversation discusses the effectiveness of adding RCP (redensyl, capixyl, procapil) to a hair loss treatment regimen that includes minoxidil and finasteride. Users share experiences, suggesting RCP may not be as effective as minoxidil, but could be useful for creating topical solutions.

      community Has anyone tried latanoprost+microneedle?

      in Microneedling  2 upvotes 2 years ago
      Microneedling combined with latanoprost may convert vellus hairs to transitional or terminal hairs. The user suggests using oral minoxidil to increase vellus hair, then applying a high concentration of latanoprost with microneedling for conversion.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 7 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 5 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community About the CBD regrowth study : just a few remarks

      in Research/Science  167 upvotes 4 years ago
      CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

      community Bryan Johnson used a customized formula by Roots byGA to restore his hair

      in Treatment  26 upvotes 1 year ago
      Bryan Johnson used a customized hair restoration formula from Roots byGA, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. Many users are skeptical of the effectiveness and uniqueness of the treatment, suggesting that standard treatments like Minoxidil and Dutasteride are more reliable.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 3 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.

      community Pyrilutamide (KX-826) progress?

      in Is this regrowth?  20 upvotes 1 year ago
      The user has been using pyrilutamide 0.5% for over 7 weeks, alongside dutasteride, and noticed some hair improvement, particularly at the temples. They plan to continue and possibly try a 1% solution, with no shedding or side effects reported.

      community 2.5mg dut safety/price/synergy w/topical fin

      in Finasteride/Dutasteride  3 upvotes 2 years ago
      The conversation discusses the safety and cost of 2.5mg Dutasteride, and the potential for increased DHT reduction by combining Dutasteride with topical Finasteride. The original poster is currently using 0.5mg Dutasteride, 1.25mg oral Minoxidil, and a topical treatment, and is considering increasing the dosage to maximize results while avoiding less known treatments like RU58841.

      community oral hyaluronic acid supplements?

      in Treatment  4 upvotes 4 years ago
      Oral hyaluronic acid is not beneficial for hair, as it gets broken down in the stomach and has no strong evidence supporting its effectiveness. The user is taking finasteride, dutasteride, and topical minoxidil for hair loss, but combining finasteride and dutasteride is considered redundant.

      community Helicobacter's concocted serum v1

       8 upvotes 7 years ago
      A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

      community Adding caffeine to topical minoxidil

      in Research/Science  4 upvotes 1 year ago
      Adding caffeine to topical minoxidil is unlikely to enhance its effectiveness, with most users agreeing it has minimal impact. The main treatments discussed are minoxidil and finasteride, with some users adding other ingredients like azelaic acid and retinol.

      community Going to inject NAD+ and GHL-Cu into Scalp for a few months

      in Chat  1 upvotes 6 months ago
      The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

      community What’s the update on Pyrilutamide?

      in Chat  12 upvotes 3 years ago
      Pyrilutamide is seen as a last hope for those who can't take finasteride, with promising results reported. However, there's uncertainty about the quality and consistency of Pyrilutamide from black market sources.