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GlossaryBupropion

medication used to treat depression and aid smoking cessation

Bupropion is a medication primarily used to treat depression and to support smoking cessation. It works by inhibiting the reuptake of norepinephrine and dopamine, which are neurotransmitters involved in mood regulation and reward pathways. Commonly known by brand names such as Wellbutrin and Zyban, it is also sometimes prescribed off-label for conditions like ADHD and seasonal affective disorder.

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community Reasonable and safe stack? Bloodwork within.

in Minoxidil 1 upvotes 2 years ago

A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

community Has anyone successfully tapered off finasteride?

6 upvotes 11 years ago

A user is considering tapering off finasteride due to concerns about long-term side effects and cost, and is exploring alternatives like zinc and saw palmetto. Their current regimen includes finasteride, Adderall, zinc, bupropion, fish oil, baby aspirin, Rogaine foam, and ketoconazole shampoo.

community 4 months, oral min fin, chewable

in Is this regrowth? 428 upvotes 1 year ago

The user experienced hair regrowth using a chewable combination of oral minoxidil and finasteride without side effects, unlike when taken separately. The treatment is from Hims, and the user is satisfied with the progress, especially on the crown.

community 24F - AGA & TE since 14. Is this regrowth for sure?

in Is this regrowth? 2 upvotes 5 months ago

A 24-year-old woman with AGA and TE since age 14 is questioning if her hair is regrowing or breaking. She has been using minoxidil consistently since September 2025, along with caffeine and ketoconazole shampoos, rosemary oil, and saw palmetto, and has improved her overall hair care routine.

community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 5 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

community I cannot even tolerate Nutrafol

in Product 6 upvotes 8 months ago

The user experienced side effects from finasteride and Nutrafol, opting for non-hormonal treatments like minoxidil, exercise, and a healthy lifestyle. Others discussed using Dutasteride, Biotin, and minoxidil with varying success and side effects.

community 31M. Just diagnosed with androgenic alopecia. Fears of min.

in Finasteride/Dutasteride 12 upvotes 9 months ago

A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

community There is simply no way to get finasteride in Germany

in Finasteride/Dutasteride 82 upvotes 2 years ago

A user in Germany struggles to get a finasteride prescription despite trying multiple doctors and apps, only receiving minoxidil. Other users suggest alternative sources like Zava.med, EU doctor App, and buying from pharmacies abroad.

community People who continue to lose hair on fin/dut, Are you on Nicotine?

in Research/Science 81 upvotes 1 year ago

Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.

community When I’m 60 and finally off the fin after 40 years and look at my semen

in Satire 862 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Users share experiences with Finasteride, mentioning watery semen as a side effect and weighing its importance against maintaining hair.

community has anyone heard of Wellbutrin causing hairloss??

in Chat 2 upvotes 3 years ago

Wellbutrin may cause hair loss, as several users reported increased hair shedding while on the medication, with hair regrowth observed after stopping it. Minoxidil was used by one user to help with hair loss, and turmeric was noted to thicken hair.

community Hair Loss Associated with Escitalopram (anti-depressant). Do SSRIs Affect the Hair Follicle?

in Research/Science 7 upvotes 2 years ago

A 22-year-old male experienced hair loss potentially linked to escitalopram, which stopped after switching to vortioxetine. His depressive symptoms improved with continued treatment.

community RU-58841 Experience (15mg daily dissolved in stemoxydine)

in Treatment 14 upvotes 4 years ago

User experienced reduced hair loss with 15mg RU in Serioxyl but had concerning chest pain. Others suggested consulting a doctor or lowering the dose.

community How an SSRI seemed to help my hairloss

in Chat 7 upvotes 3 years ago

An SSRI (paroxetine) reduced hair loss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hair loss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hair loss.

community Any adderall / vyvanse users here?

in Chat 1 upvotes 3 months ago

Adderall and Vyvanse may contribute to hair loss by stressing the dopamine system and increasing cortisol levels. Users discuss potential treatments like Minoxidil, finasteride, and RU58841 for managing hair loss.

community CB-03-01 / Breezula Personal Results

in Treatment 17 upvotes 4 months ago

The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

community EMA is re-examining Winlevi (clascoterone at lower concentration)

in Treatment 8 upvotes 11 months ago

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

community Depression, ADHD meds and Finasteride

in Finasteride/Dutasteride 1 upvotes 1 year ago

Finasteride caused anxiety, depression, and hair shedding for the user, leading them to stop taking it. They are now on Lexapro and Adderall for depression and ADHD, and are considering trying topical Finasteride and Minoxidil.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 3 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Don’t get too hyped up about Breezula, it‘s not a wonder drug

24 upvotes 7 years ago

The conversation discusses skepticism about Breezula, a hair loss treatment, with the consensus that it's not a miracle cure but a maintenance drug that may work well with finasteride. Some users report side effects from finasteride, like sexual dysfunction, while hoping for better results from Breezula or RU58841 without such side effects.

community Switching from Finasteride to RU58841?

in General 168 upvotes 9 months ago

The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.

community Clascoterone/ Breezula will it work

in Research/Science 2 months ago

Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

community Beneficial supplement (my experience)

in Product 1 upvotes 5 months ago

The user shares their experience with hair loss treatments, specifically finasteride, and discusses the side effects like lowered libido and motivation. They recommend trying tyrosine to counter these effects, noting it improved their libido and energy levels.

community Pyrilutamide: Increased libido. Anyone else experienced something similar with either RU or Pyri?

in Product 18 upvotes 3 years ago

An increase in libido associated with the use of Pyri, and a discussion about how it may be working comparably to other hair loss treatments such as RU58841, Finasteride and Minoxidil.

community Joining clinical study for Clascoterone (Breezula)

in Research/Science 7 upvotes 1 year ago

The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

community Pyrilutamide Phase 3 on its way

in Treatment 128 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community RU/Pyrilutamide access and purchase

in Product 3 upvotes 5 months ago

The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

community Finasteride 5mg & Spironolactone 100mg

in Female 2 upvotes 1 year ago

A 20-year-old female is using finasteride 5mg and spironolactone 100mg for severe hirsutism and is experiencing minor side effects like water weight loss and irregular periods. She is concerned about potential future side effects and hair regrowth on her scalp.

community Is it Ritalin? (23 F)

in Question 6 upvotes 6 years ago

A user suspects Ritalin is causing hair loss due to vasoconstriction and is considering trying Ginkgo Biloba after already taking a multivitamin and hair supplement. Another user mentions experiencing hair shedding with Vyvanse and Dexedrine.

community RU58481, are side effects exegerated?

in Treatment 4 upvotes 4 years ago

RU58841's side effects may be exaggerated due to anxiety, with some users experiencing no issues and others reporting symptoms like chest pain. RU58841, minoxidil, and finasteride are used for hair loss treatment, with varying individual reactions.