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      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Does Peppermint oil have a shedding phase?

      in Treatment  6 upvotes 3 years ago
      A user has been using peppermint oil with caffeine on their scalp and is experiencing more visible scalp, questioning if it's a shedding phase or ineffective treatment. Another person suggests the peppermint oil is not working and the user is naturally losing hair, implying that more established treatments like minoxidil or finasteride would be preferred.

      community Question about topical part of treatment

      in Treatment  2 upvotes 1 year ago
      The user is using a combination of oral Dutasteride and Minoxidil, and a topical formula with Finasteride, Minoxidil, and Hydrocortisone, along with rosemary oil, coconut oil, ginseng, and a derma roller. They are also using LLLT therapy and are questioning the timing of the laser cap session in relation to the topical application.

      community Anagenic is trying to compound Gt20029

      in Treatment  55 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community Liquid minoxidil + pyrilutamide

      in Treatment  17 upvotes 3 years ago
      Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

      community cant use minoxidil, is there anything else that can mimic the results?

      in Treatment  6 upvotes 1 year ago
      The conversation is about alternatives to minoxidil for hair growth, as the original poster experienced chest tightness from using it. They are currently using finasteride and considering options like rosemary oil, pumpkin seed oil, and other topical treatments, but acknowledge that minoxidil and finasteride are the most scientifically supported treatments.

      community Topical latanoprost chance of eye color change?

      in Product  1 upvotes 1 year ago
      The user is using oral minoxidil for hair growth and is considering adding topical latanoprost, but is concerned about potential eye color change. They are seeking advice on the effectiveness of latanoprost for hair thickening and the risk of eye color change.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Problem with Topican Finasteride, sides

      in General  119 upvotes 5 months ago
      The user experienced side effects like shallow breathing, loss of libido, and erectile issues after using topical finasteride with minoxidil for hair loss. They are considering whether to continue the treatment despite these side effects.

      community Does RU58841 in Glycerin works?

      in Product 3 months ago
      RU58841 in glycerin may cause less irritation than in PG form, but its effectiveness might be reduced. Users discuss the potential trade-off between irritation and efficacy.

      community Progress finasteride and minoxidil + problem

      in Progress Pictures  2 upvotes 1 year ago
      The user is experiencing hair improvement in the central and back areas after using finasteride, minoxidil, and a galenic lotion, but the temple area is worsening. They suspect the lotion might be causing the issue and are considering stopping its use.

      community Quercetin got rid of my scalp soreness

      in Chat  3 upvotes 9 months ago
      Quercetin reduced scalp soreness and may help with histamine-related hair loss. The soreness felt like inflamed follicles beneath the scalp surface.

      community Almost 3 weeks on Pyrilutamide-Update

      in Update  12 upvotes 3 years ago
      The user has been using Actifolic Pyrilutamide 0.5% once daily for almost three weeks without noticing any side effects or progress. Other users suggest that significant results typically take 3-6 months to appear.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 2 years ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.
      Brutal shedding after switching to oral min

      community Brutal shedding after switching to oral min

      in Minoxidil  48 upvotes 1 month ago
      Switching from topical to oral minoxidil caused heavy shedding and thinner, brighter hair. The user is seeking advice on whether hair can recover to its previous state.

      community biotin leads to acne and sebum on scalp ??

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      User is experiencing increased sebum, dandruff, and acne after taking a supplement containing biotin, iron, zinc, and calcium pantothenate along with finasteride. They are questioning if biotin is the cause and whether they should stop taking it.

      community Switching from Oral Minoxidil back to topical

      in Treatment  9 upvotes 1 year ago
      Switching from oral minoxidil back to topical due to heart issues and palpitations. Users discuss experiences with minoxidil and finasteride, with mixed results and concerns about side effects.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community Microneedling leaves scalp red for days

      in Microneedling  7 upvotes 4 years ago
      Woman with AGA uses microneedling, minoxidil, spiro, and laser for hair loss. Experiences redness and tenderness for three days after microneedling with Dermapen M8, asks if it's normal and the correct speed setting.

      community Important reminder for cat owners ⚠️

      in Minoxidil  441 upvotes 9 months ago
      Minoxidil is extremely toxic to cats, even in small amounts, and can be fatal. Switching to oral minoxidil is safer for cat owners, but precautions should still be taken to prevent exposure.