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      community I’m considering stopping finasteride

      in Finasteride/Dutasteride  157 upvotes 3 months ago
      The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 5 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  32 upvotes 9 months ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 2 years ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community 1 year Progress: Fin + Oral Min 5mg

      in Progress Pictures  407 upvotes 3 years ago
      A user's experience with finasteride and oral minoxidil for treating hair loss, which resulted in great regrowth and improved mental state. Other users asked questions about their own experiences with the treatments.

      community Please stop looking for a natural way to stop your hairloss

      in Chat  247 upvotes 4 years ago
      There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

      community Not balding just low density hair

      in Styling  562 upvotes 6 days ago
      A person with low-density hair likely experiencing diffuse thinning. Suggested treatments include finasteride, minoxidil, and dutasteride.

      community Oral minoxidl is very very powerful.

      in Chat  585 upvotes 3 weeks ago
      Oral minoxidil is more effective than topical minoxidil for hair regrowth but may cause side effects like heart issues and increased body hair. Combining it with finasteride is common for better results, though side effects vary.

      community Been on min+fin for 2 years, only gotten worse. B/A pics included

      in Chat  88 upvotes 2 months ago
      The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.

      community He is claiming, he can treat alopecia

      in Chat  357 upvotes 3 months ago
      A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

      community Solution for male pattern baldness

      in Treatment  243 upvotes 4 months ago
      A new hair loss treatment claims a 539% improvement over placebo, but skepticism remains due to lack of substantial evidence and reliance on percentage figures. Users discuss the effectiveness of existing treatments like Minoxidil and Finasteride, expressing doubt about the new solution's impact.

      community Almost 7 months of Topical Fin + Min

      in Progress Pictures  346 upvotes 4 months ago
      A 24-year-old shared their 7-month progress using a topical solution of finasteride 0.1%, minoxidil 5%, and hydrocortisone butyrate 0.08%, along with ketoconazole shampoo, to treat hair loss, reporting no side effects and noticeable hair improvement. They also take vitamin D and biotin supplements, use a dermastamp, and manage Hashimoto's without thyroid medication.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  229 upvotes 5 months ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community 25M 4 months Fin + oral Min keep hope

      in Progress Pictures  230 upvotes 5 months ago
      A 25-year-old male shared his hair loss journey, using finasteride and oral minoxidil, which improved his hair density and quality. He also addressed dermatitis with exfoliation and anti-dandruff shampoo, and emphasized the importance of a healthy scalp and lifestyle changes.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  457 upvotes 7 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.