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After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

GT20029 and pyrilutamide are both androgen antagonists but work differently; GT20029 degrades the androgen receptor, while pyrilutamide blocks DHT from binding. GT20029 is expected to have similar efficacy to CosmeRNA.

A user shared a 10-month update on their hair transplant (HT), expressing significant confidence gain and recommending the procedure to others. They had the transplant in Turkey for $2300 and are very satisfied with the results.

The user has been using oral finasteride for over a year and recently added GHK-CU for two months, seeing progress but seeking further improvement, especially on the hairline. They discuss sourcing GHK-CU, its effects, and the importance of third-party testing, while considering additional treatments like dutasteride and hair transplants for better results.

A user successfully managed finasteride-induced gyno symptoms by making lifestyle changes, including fasting, avoiding soy, and increasing cardio. They resumed finasteride with a lower dose combined with minoxidil and P7 vitamins without recurrence of symptoms.

The user is experiencing hair loss with possible causes including chronic telogen effluvium, diffuse alopecia areata, and androgenic alopecia. They have tried treatments like Nizoral shampoo, minoxidil, and finasteride, and are considering a biopsy for further clarity.

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

A 21-year-old male is using a Minoxidil (10%) and Finasteride (0.1%) topical solution with a Keraglo Men tablet for hair loss, experiencing positive results without side effects. He advises another user to prepare questions for a dermatologist visit and discusses potential treatment adjustments.

A 24-year-old male experiencing diffused thinning discusses his DHT levels and hair density issues. He has not used finasteride or dutasteride and is considering AR inhibitors.

An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.

A user shared their 9-month progress using Propecia and minoxidil for hair loss, noting significant daily shedding. Others suggested potential vitamin/mineral deficiencies and offered encouragement.

A 39-year-old user experienced hair regrowth using oral dutasteride, oral minoxidil, dermastamping, and Nizoral shampoo after switching from finasteride and topical minoxidil. They are hopeful for significant improvement in their receding hairline.

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

OP experienced significant hair regrowth after recovering from iron deficiency anemia and starting minoxidil. They suspect anemia contributed more to their hair loss than androgenetic alopecia (AGA).

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

The user has been using finasteride, minoxidil, and ketoconazole for hair loss, showing good progress without significant side effects. They plan to have a hair transplant in March and hope to eventually stop using oral minoxidil.

The user is using finasteride 1mg daily for one month and ketoconazole three times a week for three months. They are comparing hair progress with photos from December 2025 and March 2026.

The conversation discusses hair regrowth progress using finasteride, minoxidil, dutasteride, ketoconazole, microneedling, and multivitamins. The user shares their journey and receives advice on haircuts and additional treatments like PRP and RU58841.

A 19-year-old male is experiencing positive hair regrowth results after four months of using finasteride, minoxidil, and biotin. Others express admiration and share their own experiences with hair loss treatments.

A 26-year-old has been using finasteride for over two years, initially at 1.25mg daily and later at 5mg weekly, resulting in stable hair condition with some regrowth and minimal side effects. The user reports high libido and a protein and vegetable-heavy diet, with initial watery semen as the only side effect.

A 21-year-old male has been using finasteride for 8 months to address hair loss and is starting to track progress with photos. He plans to update with more progress pictures in the future.

The user experienced significant hair regrowth after using 1.25mg finasteride for 7 months, with no side effects, and is considering whether to keep or remove a previous SMP (scalp micropigmentation). They avoided minoxidil due to dandruff and sensitive scalp concerns, and they use a specific dandruff shampoo once a week.

The user "_Mad_Jack_" shared their progress pictures of using topical finasteride and minoxidil for 11 months. They experienced good hair retention and increased overall hair count, but no regrowth of the hairline. They are considering switching to oral finasteride and microneedling for better results. Testicular pain was a side effect experienced during the treatment. Another user mentioned getting a hair transplant to cover their crown.

The user has high DHT levels despite using dutasteride, which may not be effective due to potential damage or spoilage. They are considering a hair transplant if DHT levels don't decrease after two years.

A user's 18-month hairline progress using minoxidil, finasteride, Nizoral, microneedling, and scalp massage. They share their routine and discuss treatment effectiveness and photo order confusion.