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      community A little optimism post to detract from all the doom posting.

      in Technology  11 upvotes 2 months ago
      A user shares optimism about combating male pattern baldness using oral and topical minoxidil, highlighting the advancements in treatments available today. Another user agrees, noting that early treatment can yield good results, and mentions the availability of affordable hair transplants.

      community Forgot min+fin whilst travelling

      in General  82 upvotes 1 year ago
      The user forgot their minoxidil and finasteride while traveling in Indonesia and is concerned about hair loss. They are advised that a 6-week break might cause some shedding but not drastic changes, and it's safer to wait for friends to bring the medication due to strict drug laws.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community RootBioTec? Basil extract for hair growth

      in Product  4 upvotes 1 year ago
      RootBioTec, a basil hairy root extract, claims to reduce hair loss by 31% in two months by inhibiting 5α reductase II and stimulating hair follicles. There is limited independent information available about its effectiveness.

      community Finasteride and Ketoconazole 2%, 13 months update (Amazing results)

      in Finasteride  21 upvotes 8 years ago
      A user shared their 13-month experience using finasteride and ketoconazole 2%, reporting significant improvement in hair growth, especially in the crown and temple areas. They also mentioned occasional use of biotin, multivitamins, and zinc, but noted recent increased shedding and hair loss in unexpected areas.

      community 23M 5 month minox+fin+dermaroll

      in Progress Pictures  27 upvotes 2 years ago
      The conversation is about a 23-year-old man's 5-month progress using minoxidil, finasteride, and dermarolling to treat hair loss, with before and after photos taken in the same location and lighting. One commenter notes difficulty in assessing the improvement due to the way the hair is combed over the bald spots.

      community Duoxidil / Dutasteride/ Minoxidil

      in Minoxidil  83 upvotes 1 year ago
      The conversation discusses a user's positive experience with hair loss treatments, including Duoxidil, oral Dutasteride, oral Minoxidil, and biotin, noting no side effects and effective results. The user plans to start a new cycle of Dutasteride and PRP sessions.

      community Will you try clascosterone when it gets released?

      in Treatment  14 upvotes 4 months ago
      People are interested in trying clascosterone (Breezula) for hair loss, especially those who are too young for finasteride. Some users express concerns about the cost and prescription requirements, while others discuss alternatives like RU58841.

      community Is there any new drug that looks promising ?

      in Research/Science  26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Using the nuclear stack and still losing hair... Is this the end for my hair?

      in Update  4 upvotes 3 years ago
      The user is experiencing ongoing hair loss despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, cyproterone acetate, transdermal estradiol, and topical bicalutamide. They suspect cyproterone acetate may be worsening their hair loss and are considering switching to injection monotherapy.

      community Funny Encounter With a Mechanic - Hair Loss Update

      in Update  39 upvotes 2 months ago
      The user has been taking 3.75mg of finasteride weekly for 8 months, which has improved their hairline and hair texture. They shared a humorous encounter with a bald mechanic who complimented their hair, unaware of the finasteride use.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community 3 month progress on Manual combi fin/min pill

      in Progress Pictures  19 upvotes 1 year ago
      A user shared their 3-month progress using a combined finasteride and minoxidil pill for hair loss, noting early signs of regrowth. They also use biotin shampoo/conditioner, take Vyvanse and Propranolol, and bleach/dye their hair every 3 weeks.

      community Any active Kx-826 Pyrilutamide group buys happening?

      in Product  11 upvotes 4 years ago
      The conversation discusses organizing group buys and tracking progress for Kx-826 Pyrilutamide, a hair loss treatment. Participants express optimism about upcoming results and concerns about self-reporting bias.

      community 1 year oral fin (1.1 mg) and oral min (3 mg)

      in Progress Pictures  375 upvotes 1 year ago
      The user shared a one-year update on using oral finasteride (1.1 mg) and oral minoxidil (3 mg) along with ketoconazole shampoo, reporting significant hair regrowth and satisfaction with the results despite some side effects like thicker eyebrows and chest hair. The user encourages others to start treatment early and plans to continue the current regimen for further improvement.

      community Hair follicle cloning is already possible

      in Chat  38 upvotes 1 year ago
      Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

      community Back from the dead... (sort of)

      in Progress Pictures  11 upvotes 9 months ago
      A 25-year-old shares progress on hair regrowth using finasteride, ketoconazole shampoo, Alpecin caffeine shampoo, and topical minoxidil, noting improved hair health but persistent temple thinning. They consider switching to oral minoxidil, adding microneedling, and possibly a hair transplant after one year.

      community Don't leave a boy hanging, try to help.

      in Chat  113 upvotes 1 year ago
      A user shared their success with oral finasteride and topical minoxidil for hair loss, recommending these treatments to others. They emphasized the importance of informing others about effective treatments rather than relying on supplements.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  128 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.