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      community cb-03-01 research chem (winlevi/clascoterone cream)

      in Technology  3 upvotes 2 years ago
      The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community Mineral deficiencies vs MPB vs Thyroid

      in Chat  9 upvotes 1 year ago
      The user experienced hair improvement using a topical finasteride, minoxidil, and tretinoin combo, along with supplements like zinc, copper, magnesium, vitamin D3, K2, iodine, and boron. They believe these changes are due to addressing mineral deficiencies and possibly thyroid issues, despite skepticism from others.

      community Fin/Min/VitD 6 Month Progress Pics

       7 upvotes 7 years ago
      The user shared a 6-month update on their hair loss treatment using finasteride, minoxidil, Nizoral shampoo, and vitamin D. They reported progress but mentioned possible sexual side effects and recent shedding, seeking advice on adjusting their finasteride dose.

      community Haircafe video on Min Sulfate, thoughts?

      in Research/Science  101 upvotes 7 months ago
      Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.

      community Which vitamin deficiencies can lead to hair loss?

      in Chat  69 upvotes 3 years ago
      The conversation discusses potential vitamin deficiencies leading to hair loss, with a focus on Vitamin D and iron. Some individuals are using finasteride and minoxidil for hair loss, while others consider vitamin supplementation due to deficiencies.

      community I got my bloodwork done... What now?

      in Update  6 upvotes 5 months ago
      The user has been experiencing hair thinning despite taking finasteride and minoxidil for six months. Bloodwork suggests a vitamin D deficiency, and users recommend consulting a doctor and possibly supplementing vitamin D.

      community Success: My Doc prescribed me 0.1% Alfatradiol

      in Treatment  13 upvotes 1 year ago
      A user shared their success in getting a prescription for 0.1% Alfatradiol, a topical treatment for hair loss similar to finasteride but with fewer side effects. They found a pharmacy to compound it and will update on the results.

      community Multivitamin recommendations?

       2 upvotes 10 years ago
      The conversation is about hair loss treatments and multivitamin recommendations. The user mentions Minoxidil, finasteride, RU58841, biotin, procyanidin B-2, floral oils, and Viviscal.

      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 3 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Does anyone use alfatradiol? Does it do anything at all??

      in Treatment  6 upvotes 4 weeks ago
      Alfatradiol is considered a mild treatment for hair loss, often used alongside other treatments like finasteride, minoxidil, and dutasteride. Users report it helps maintain hair but is not effective for regrowth on its own.

      community Got sides on fin, now Alfatradiol or Fluridil?

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      The user experienced side effects from finasteride and is considering adding Alfatradiol or Fluridil to their regimen, which includes Minoxidil, dermarolling, and ketoconazole. Fluridil is noted to be more effective than Alfatradiol but less effective than finasteride, with mild side effects reported.

      community Can’t take fin - options/alts?

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.

      community How to effecively mix alfatradiol and finasteride tablets?

      in Treatment  2 upvotes 2 years ago
      The user is using a mixture of crushed finasteride tablets and alfatradiol as a topical treatment for hair loss, applying 1 ml daily, and is asking if this is an effective method or if alfatradiol is a suitable solvent. They mention that others often mix finasteride with minoxidil, but they want to try without it.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Looking for suggestions on vitamins

      in Female  6 upvotes 2 years ago
      A user is seeking affordable hair vitamins without biotin, already taking zinc and D3+K2, and has been dealing with chronic telogen effluvium since 2013. They previously used Nutrafol Vegan but found it too expensive.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  58 upvotes 2 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.