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      community Nizoral ketaconazole any good for dht reduction

      in Ketoconazole  8 upvotes 5 years ago
      A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Nanoxidil Spectral.DNC-n 60ml.

      in Treatment  1 upvotes 2 years ago
      A user recently started using nanoxidil 5% for hair loss, particularly on the hairline, and is seeking feedback or experiences from others. The conversation focuses on the effectiveness of nanoxidil.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 2 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 3 months ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community Best minoxidil formulation for best results?

      in Minoxidil  2 upvotes 1 year ago
      The conversation discusses creating a customized minoxidil formulation with tretinoin, azelaic acid, and caffeine, but there are concerns about foam stabilization due to acidity. The user seeks advice on the best formulation for effective results.

      community What has the evidence been on side effects with CB?

      in Research/Science  4 upvotes 5 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.

      community Does anyone here use MVSupplements.con products?

      in Product  1 upvotes 8 months ago
      The conversation discusses concerns about MVSupplements.com products, specifically the Min+Ru spray and GHK Serum, due to discrepancies in ingredient lists and recent poor feedback. Users also mention a price increase and one user reports no issues with the RU powder.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  14 upvotes 2 years ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  15 upvotes 3 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community Cosmo Pharma 2025 Investor Day Report

      in Research/Science  7 upvotes 11 months ago
      Cosmo Pharma plans to release Breezula, a hair loss treatment, with expected FDA approval in 2027, but concerns arise over its high potential cost of $225/month. Users express skepticism about its effectiveness compared to cheaper alternatives like finasteride and minoxidil.

      community Nordic biolabs Stem cells = Apple Stem Cells

      in Product  5 upvotes 1 year ago
      A new hair growth product claims to use apple stem cells, plant collagen, and bamboo leaf extract, with a 120-day money-back guarantee. Some users are skeptical, noting the product's marketing alongside other treatments like Minoxidil, finasteride, and red light therapy.

      community Couple of questions for hair fiber users

      in Product  6 upvotes 4 years ago
      User plans to use hair fibers regularly and asks about re-application, consistency, rain protection, and Boldify vs Toppik. Others provide advice and share experiences.

      community CB-03-01 users come forward!

       13 upvotes 6 years ago
      The conversation discusses the potential of a new hair loss drug, CB-03-01, with users sharing their experiences and seeking advice on dosages and application methods. One user mentions using topical finasteride, minoxidil, dermarolling, and a clean diet for hair maintenance but is interested in CB-03-01 due to side effects from finasteride.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

      in Product  1 upvotes 9 months ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community What’s needed to mix ru and k&b solution?

      in Research/Science  2 upvotes 1 year ago
      Mixing RU58841 with a solution for hair loss treatment, with suggestions to use propylene glycol and ethanol instead of k&b solution due to scalp irritation. Recommendations include using ketoconazole shampoo for itchiness and considering oral minoxidil if topical causes irritation.

      community Put P5P in my shampoo, reduced itch a lot!

      in Chat  4 upvotes 3 years ago
      The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.

      community Anyone have any KX-826 results yet?

      in Product  14 upvotes 1 year ago
      KX-826 users report increased shedding, with some experiencing more shedding at higher concentrations. Users are discussing where to purchase the product.

      community Source for Pyrilutamide has disappeared

      in Treatment  21 upvotes 3 years ago
      Anageninc stopping the sale of Pyrilutamide due to a cease and desist order from Kintor, with some speculating that it was either a hoax or subpar product.

      community Which conditioner do you use along with Nizarol?

      in Ketoconazole  7 upvotes 3 years ago
      The conversation is about finding a suitable conditioner to use with Nizoral, a ketoconazole shampoo. One person is trying a caffeinated/coconut conditioner to strengthen hair but hasn't seen results yet.