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      community Going to start the sulforaphane experiment

      in Treatment  18 upvotes 4 years ago
      A user shared their experience with hair loss treatments, including minoxidil and finasteride, and their negative side effects. They outlined a new treatment plan involving microneedling, various supplements, minoxidil foam, ketoconazole shampoo, and an anti-inflammatory diet, with plans to document progress over three months. Another user responded, indicating their own similar efforts were a waste of money.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Ketoconazole shampoo, which one to choose??

      in Ketoconazole  6 upvotes 4 months ago
      Ketoconazole shampoo is recommended at a 2% concentration for hair loss, with advice to leave it in the hair for 2-5 minutes. Users discuss different brands, noting that Nizoral contains artificial dyes, and suggest alternatives without dyes.

      community Does creatine increase DHT/cause hair loss?

      in Research/Science  22 upvotes 3 years ago
      Creatine is reported to cause increased hair shedding, but there is no scientific evidence linking it to hair loss. Some users manage hair loss with finasteride and minoxidil or consider stopping creatine if shedding worsens.

      community 2.5 Months on Fin/Min/Keto/Microneedling (The Big 4)

      in Is this regrowth?  8 upvotes 2 years ago
      The user discusses their hair loss treatment routine using Minoxidil, Finasteride, microneedling, and Ketoconazole shampoo. They report initial side effects from Finasteride but believe the treatment is working and seek opinions on their progress.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community Anyone tried GHK-CU for hair loss?

      in Treatment  6 upvotes 9 months ago
      The conversation is about using GHK-Cu, a copper peptide, for hair loss treatment. Users discuss their experiences, dosages, and additional benefits like improved skin and energy.

      community EssenGen 6-Plus with PG Results - 7 Weeks

      in Progress Pictures  160 upvotes 5 months ago
      The user started using EssenGen 6-Plus, containing 6% minoxidil and 0.05% finasteride, along with 1% Nizoral shampoo, and reported noticeable hair growth in 7 weeks. They experienced some chest tightness but are monitoring it, and they are satisfied with the progress despite using a silicone-containing shampoo.

      community Why hasn’t anybody or any company done experiments on whether minoxidil and finasteride have effects on human collagen and elastin after a year of use compared to placebo? (In vivo not vitro)

      in Research/Science  4 upvotes 2 months ago
      The conversation discusses the lack of in vivo studies on the effects of minoxidil and finasteride on human collagen and elastin after a year of use. It highlights the potential benefits of such research for understanding side effects and improving sales, despite challenges like cost and competition.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 10 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  36 upvotes 8 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Copper Peptides—Discussion

       5 upvotes 7 years ago
      Copper peptides, specifically GHK-Cu, are discussed as a potential addition to hair loss treatments, possibly working synergistically with Minoxidil to convert vellus hair into terminal hair. The effectiveness and credibility of copper peptides are questioned due to the lack of widespread discussion and potential conflict of interest from the product's creator.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  19 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

      in Treatment  6 upvotes 3 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community Turkey? Fin? Min? Fin+Min? Biotin? Keto? Saw? Dut? Nut?

      in Satire  1350 upvotes 4 months ago
      Hair loss treatments and celebrity hair maintenance, mentioning finasteride, minoxidil, RU58841, biotin, ketoconazole, saw palmetto, dutasteride, and Nutrafol. The tone is satirical, speculating on celebrities' use of hairpieces and transplants.

      community Keto shampoo and its impact on dht levels?

      in Progress Pictures  5 upvotes 9 months ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is considered a mild topical antiandrogen. Users discuss its use for scalp health rather than DHT reduction, with some preferring alternatives like dutasteride over finasteride due to perceived side effects.