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240-270 / 1000+ resultscommunity 2 % fucoidan significantly alleviated AGA symptoms, promoted hair growth, and increased hair density
2% fucoidan alleviated AGA symptoms, promoted hair growth, and increased hair density in mice. Fucoidan is considered safe for humans as a supplement and topical skincare product, with potential therapeutic effects against AGA.
community Verteporfin and BPC-157: Hair Loss Cure Stack?
Verteporfin and BPC-157 are being discussed as potential treatments for hair loss. The conversation also mentions Minoxidil, finasteride, and RU58841.
community Any good experiences with Alfatradiol ?
Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.
community Minoxidil and Caffeine - opposite effects yet comboed together?
Minoxidil and caffeine are discussed for hair loss treatment. The user questions the logic of combining them due to their opposing effects on adenosine receptors.
community Just a rule of thumb regarding "the cure™"
Be skeptical of claims about new baldness cures; current treatments like finasteride, dutasteride, and minoxidil remain the best options. New products like Breezula and PP405 lack compelling evidence and may not be available soon.
community Pyrludimide (KX-826) or Breezula (clascoterone)
The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.
community Theoretically won't this be better than finasteride? Azelaic acid + zinc
The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.
community MY ANECDOTAL REPORT ON SAFETY OF ALFATRADIOL AND FLURIDIL COMBINED WITH FINASTERIDE! COMPOUNDS APPROVED FOR MPB IN THE EUROPEAN UNION (i cant comment on the efficacy, cause i am on other treatments)
The safety of combining alfatradiol and fluridil with finasteride as a potential treatment for male pattern baldness, which is approved in the European Union. Other treatments such as minoxidil and RU58841 were also discussed.
community What do you think about this galenic lotion by my trichologist?
The user discusses a galenic hair lotion containing progesterone, estradiol, cyproterone, hydrocortisone butyrate, and cetirizine pheniramine, which has effectively stopped their hair loss over two years. They are curious about the compatibility of finasteride with the lotion's components and note that their trichologist has successfully used minoxidil and finasteride in similar treatments for others.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community What do you guys use before applying keto?
Keto 2% can dry out hair, especially wavy or curly types. Users suggest using oils like olive, coconut, or argan, and following up with a good conditioner or hair mask to maintain hair health.
community Minoxidil hack PSA for you all
Switching from liquid to foam Minoxidil to avoid scalp irritation, with a method to melt the foam for easier application. Users discuss alternatives and personal experiences with Minoxidil, including issues with propylene glycol and different application methods.
community Shampoo and conditioner to help get rid of dandruff? What about treatments?
The conversation is about finding effective shampoos and conditioners for dandruff, excluding ketoconazole. The user mentions trying Paul Mitchell Tea Tree shampoo and Purology, and seeks at-home treatment recommendations.
community shampoo with piroctone olamine in US?
The conversation is about finding a reasonably priced shampoo with piroctone olamine in the US. The user is cautious about trying new or smaller brands.
community What’s needed to mix ru and k&b solution?
Mixing RU58841 with a solution for hair loss treatment, with suggestions to use propylene glycol and ethanol instead of k&b solution due to scalp irritation. Recommendations include using ketoconazole shampoo for itchiness and considering oral minoxidil if topical causes irritation.
community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )
The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.
community Hydrocortisone helps with itch
Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.
community Why plain Azelaic acid is a safe and effective product for hairloss that makes Finasteride an obsolete treatment for male pattern baldness.
The conversation discusses the effectiveness of Azelaic acid for hair loss, suggesting it may make Finasteride an outdated treatment for male pattern baldness. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
community How long are Pelage going to milk the phase 2a results of PP405?
PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.
community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?
The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.
community Pp405 full presentation on new topical
A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.
community RU55841 premixed solution vs powder
RU58841 treatment for hair loss, comparing premixed solutions to powder form. Users prefer powder for cost-effectiveness and customization.
community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle
This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.
community Predicted Breezula format? (liquid/cream/foam etc)
The conversation is about the potential format of Breezula, a hair loss treatment, and concerns that it might be greasy or sticky. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.
community Soundwaves & Electricity Grows Hair? | Peptide Delivery Model.
Iontophoresis and sonophoresis can enhance drug delivery into the scalp. Combining these methods may improve the effectiveness of topical treatments like dutasteride and certain peptides.
community Anyone else get a whitish residue buildup on their temples from minoxidil/fin spray?
A user experiences a whitish residue buildup on their temples from using a compounded minoxidil and finasteride spray. Suggestions include ensuring a clean scalp before application, adjusting timing, using a moisturizer, and considering oral treatments to avoid residue.
community This seems to be working for me (New Nordic - Hair Gro, Shea Moisture Jamaican Black Castor Oil Leave in Conditioner, and NAC)
A user shared their successful hair loss regimen, which includes New Nordic Hair Gro vitamins, Shea Moisture Jamaican Black Castor Oil Leave-In Conditioner, and NAC supplements. They reported reduced hair shedding, thicker hair, and improved hair texture.
community Monoxidil treatment after 8months 10 days
community Targeting multiple AGA mechanisms with commonly available substances
The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.