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      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community Anti androgen shed all over scalp

      in Treatment  3 upvotes 2 years ago
      The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.

      community No hair, don't care! [24/F] :)

       60 upvotes 10 years ago
      A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

      community Dr. Tsuji Hair Cloning Exclusive Interview

      in Research/Science  18 upvotes 10 months ago
      Hair cloning for hair loss is unlikely to be available or affordable in the next 10 years. Current treatments like Minoxidil, finasteride, and RU58841 are still the main options, with skepticism about new advancements.

      community Pyrilutamide update: three months

      in Update  33 upvotes 3 years ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  214 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community The curious case of John Cazale’s hair

      in Satire  322 upvotes 1 month ago
      John Cazale's hairline showed strong recession at the temples but maintained solid volume and density, sparking discussion on different hair loss patterns and the importance of overall hair density. Treatments like Minoxidil and Spironolactone were mentioned as potential factors in maintaining hair, though genetics and styling were also considered significant.

      community Dr. Bloxham's Verteporfin Trial

      in Research/Science  29 upvotes 2 years ago
      Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

      community Today was Last update on pp405

      in Research/Science  108 upvotes 10 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 6 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Ru58841 for a female w male pattern baldness

      in General  166 upvotes 1 year ago
      A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

      community Wimpole Clinic 1850 grafts (23yo) Dr Malkani

      in Progress Pictures  123 upvotes 1 year ago
      A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 1 year ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  330 upvotes 10 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community Going from near slick to cowlick

      in Progress Pictures  126 upvotes 1 year ago
      The user experienced significant hair regrowth using finasteride, minoxidil, and a 4,000-graft hair transplant performed by Dr. Nader in Reynosa, Mexico. The results were natural-looking, and the user plans a second transplant for additional density if needed.

      community Serum containing minoxidil and bimatoprost analogs

      in Product 1 year ago
      A user discusses using a serum called Dallixa, containing minoxidil-like and bimatoprost-like compounds, for hair loss and greying. The user's dermatologist advised against finasteride and suggested the serum might improve hair pigmentation.

      community 23m asian progress - minoxidil + micro + vitamin

      in Progress Pictures  38 upvotes 2 years ago
      A 23-year-old Asian male shared progress pictures after 3 months of using minoxidil, microneedling for 1.5 years, and taking vitamin supplements. Replies suggest adding finasteride or dutasteride for long-term hair maintenance.