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      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community Groundbreaking complete hair regrowth wonder drug found!!!

      in Satire  919 upvotes 10 months ago
      A satirical post humorously discusses a fictional hair regrowth drug called PP405, with users joking about its effectiveness and bizarre presentation. The conversation includes humorous reactions and references to the absurdity of the content.

      community the post about vitamin c and pH levels is legit.

      in Update  12 upvotes 4 years ago
      Using vitamin C in shampoo to adjust pH levels can improve hair health and reduce oiliness and dandruff. The user mixed vitamin C powder with conditioner, achieving positive results.

      community Recommended AHK-Cu peptide brand?

      in Treatment  1 upvotes 1 year ago
      AHK-Cu peptide is considered better than GHK-Cu for hair growth. The user is seeking recommendations for trusted AHK-Cu peptide brands with third-party testing.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

      in Product  1 upvotes 1 month ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community What makes breezula different than formula 82f?

      in Question  9 upvotes 6 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

      community Will Breezula simply be an overhyped flop?

      in Treatment  14 upvotes 4 months ago
      Breezula is seen as potentially overhyped, with concerns about its cost, effectiveness, and long-term benefits compared to existing treatments like finasteride and minoxidil. Some users believe it could complement existing treatments, while others are skeptical about its impact and prefer waiting for newer options like GT20029 and PP405.

      community Clascoterone for hair loss. Promising study.

      in Treatment  11 upvotes 5 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  14 upvotes 2 years ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Where to Buy Procyanidin B2? Legit source

      in Product  8 upvotes 2 years ago
      The conversation is about finding a legitimate source for Procyanidin B2 or Apple Extract with a clear percentage of Procyanidin B2 for making a topical solution. The user reports thicker and darker body hair after taking Oral Apple Polyphenols extract.

      community AHK-cu peptides experiences and sources to buy

      in Product  7 upvotes 1 year ago
      AHK-cu peptides are discussed for hair growth, with users comparing them to GHK-cu peptides and sharing sources to buy. AHK-cu is noted as more expensive, and users express interest in finding cheaper, reliable vendors.

      community Breezula phase 3 results where are youuuu👀

      in Satire  17 upvotes 7 months ago
      Breezula's phase 3 results are expected soon, but its release is likely delayed until 2027 or 2028. The discussion highlights the need for more hair growth stimulants like AMP-303 and PP-405, as current treatments like Dutasteride effectively stop hair loss but don't regrow hair.

      community Nutritional factors to check for apart from DHT ?

      in Chat  11 upvotes 3 years ago
      The conversation is about identifying nutritional factors that should be checked and supplemented to address diffuse hair loss, including Vitamin D, Biotin, Vitamin C, Vitamin B, Iron, Zinc, Protein, and Omega-3. No specific treatments were mentioned.

      community Predicted Breezula format? (liquid/cream/foam etc)

      in Treatment  10 upvotes 6 years ago
      The conversation is about the potential format of Breezula, a hair loss treatment, and concerns that it might be greasy or sticky. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.

      community Procyanidin B2 Supplement

      in Research/Science  14 upvotes 5 years ago
      User seeks Procyanidin B2 supplement source and asks for dosage comparison. Another user requests study details and apple type importance.

      community Dustaride and vitamins question?

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      Dustaride doesn't require avoiding any vitamins, but checking vitamin D levels and supplementing if deficient is suggested. Hair vitamins are generally unnecessary unless there's a deficiency.

      community Breezula Phase 3 confusion - did they change something?

      in Chat  9 upvotes 3 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

      community Does anyone compound their own fin topicals?

      in Finasteride/Dutasteride 6 years ago
      The conversation is about a person considering making their own topical finasteride to avoid side effects from oral use. They discuss potential methods and ingredients, including cayenne pepper extract, rosemary, and coconut oil, and seek advice on effectiveness and alternatives like light therapy or dermarolling.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community My DHT-blocking protocol, I'm exited!

       5 upvotes 6 years ago
      The post discusses a hair loss treatment regimen using saw palmetto, pumpkin seed oil extract, EGCG (green tea) extract, grape seed oil extract, rosemary oil extract, and Zix. The user plans to use these DHT-blockers and 5AR inhibitors for six months and report the results.

      community Wrap it up everyone. CB-03-01 is another failed treatment

      in Treatment  81 upvotes 7 months ago
      CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

      community When do you think Breezula will be released to the public?

      in Chat  36 upvotes 4 years ago
      The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.