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      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

      in Treatment  5 upvotes 5 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 3 years ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community 13 months post hair transplant – how does my crown look?

      in Progress Pictures  9 upvotes 2 months ago
      The user is 13 months post-hair transplant and is using 1 mg finasteride and 2.5 mg oral minoxidil. They are seeking opinions on their crown's appearance, considering switching treatments, and contemplating a second transplant due to concerns about hair density and stability.

      community Shiseido RCH-01

       5 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community What happened to Breezula ????

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses the effectiveness of a hair loss treatment called CB (Breezula) in comparison to Pyrilutamide, and its potential when combined with Finasteride. There is uncertainty about when or if phase 3 trials for Breezula will begin.

      community RU-58441 Janoshik test result of Made-In-China Supplier

      in Product  27 upvotes 6 months ago
      A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.

      community Best places to get clobetasol?

      in Product  1 upvotes 1 year ago
      The user is considering switching to oral dutasteride, topical minoxidil, retinoic acid, and clobetasol for hair loss treatment, after limited regrowth with finasteride and other topicals. They are seeking a source for clobetasol, as they believe it may help with their condition.

      community What makes breezula different than formula 82f?

      in Question  9 upvotes 6 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

      community Anyone Taking CB-03-01

       7 upvotes 7 years ago
      The conversation is about someone seeking information on long-term users of CB-03-01 for hair loss, having experienced negative side effects from finasteride and facing rapid hair thinning.

      community HNY, any word on Breezula for 2021?

      in Product  6 upvotes 5 years ago
      Breezula passed a clinical trial in August and there are questions about its availability in 2021 and potential delays due to Covid. No specific treatments were discussed.

      community Thinking about my making own CB-03-01 (Breezula). Thoughts?

      in Treatment  6 upvotes 5 years ago
      The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

      community Month 13 - Oral Fin, Top Min and Keto shampoo

      in Is this regrowth?  10 upvotes 3 months ago
      The user is using 1mg oral finasteride daily, applying topical minoxidil 1-2 times daily, and using Nizoral shampoo twice a week for hair regrowth. They are discussing their progress at month 13 of this treatment regimen.

      community Post Low-Level Laser Light Therapy Syndrome (PLLLTS )

      in Satire  6 upvotes 3 years ago
      Hair loss discussion includes LLLT treatments and a satirical condition called PLLLTS, causing patients to resemble lighthouses and attract moths. Some users express concern about others taking the satire seriously.

      community Gt20026 - the actual cure to hairloss?

      in Research/Science 2 months ago
      GT20026 is discussed as a potential treatment for hair loss that targets androgen receptors without affecting hormone levels, but it may not promote significant regrowth. It is expected to be available by 2028, with other treatments like Breezula and Clascoterone also mentioned.

      community Using 1% Clascoterone cream on hairline?

      in Chat  4 upvotes 2 months ago
      A 30-year-old man with hairline recession is considering using 1% Clascoterone cream on his hairline while awaiting a 5% Breezula product. He has been using oral Minoxidil for four years but stopped using Finasteride due to side effects.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  44 upvotes 1 month ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  57 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Breezula or kx-826 which one is better ?

      in Technology  3 upvotes 9 months ago
      Breezula (cb-03-01) and kx-826 are discussed as hair loss treatments. Kx-826 is available on Kintor's website, while Breezula is available on the grey market.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 4 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community MBP Itch CURE?/ Slow shedding TBD

      in Question  7 upvotes 6 years ago
      A user with diffuse hair loss for a decade tried various treatments, including LLLT Helmet, supplements, topicals, and hair transplants. They found relief from scalp inflammation and itching using a topical solution made from crushed Xeljanz pills mixed with ethyl alcohol.
      M20 with Hair Loss - Clascoterone an Option?

      community M20 with Hair Loss - Clascoterone an Option?

      in Basic Questions  65 upvotes 2 months ago
      A 20-year-old is experiencing hair thinning and is considering Clascoterone and Minoxidil as treatments, avoiding finasteride due to concerns about fertility and hormones. A suggestion was made to use Clascoterone for local DHT targeting and combine it with Minoxidil for maintenance and regrowth while avoiding systemic side effects.

      community Breezula Phase 3 confusion - did they change something?

      in Chat  10 upvotes 4 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

      community Don't use PP405 from everychem. it is likely fake.

      in Research/Science  66 upvotes 11 months ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community My summation of PP405 - looks promising

      in Research/Science  206 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.