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      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community How to take care of the microneedler?

      in Microneedling  7 upvotes 7 months ago
      Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

      community My DHT levels while being on DUT for a year

      in Finasteride/Dutasteride  32 upvotes 9 months ago
      The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.

      community Does caffeine inhibit 5-α-reductase?

      in Treatment  5 upvotes 6 years ago
      Caffeine may promote hair growth and potentially inhibit 5-α-reductase activity in hair follicles, but its effectiveness and systemic impact remain unclear. Users discuss using topical caffeine solutions, with some experiencing no side effects compared to finasteride.

      community RU and cetosomal minoxidil topical

      in Minoxidil  1 upvotes 2 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community PP405 bandwagon, time to resume the hype train.

      in Treatment  167 upvotes 7 months ago
      PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

      community Cure/better treatment options in the future

      in Chat  11 upvotes 1 year ago
      The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.

      community A tale as old as time, Im a finasteride D-rider btw

      in Satire  12 upvotes 1 year ago
      The conversation humorously discusses hair loss treatments, specifically mentioning the use of finasteride, minoxidil, and RU58841. The tone is satirical, with the user playfully referring to themselves as a "finasteride D-rider."

      community Can GT20029's Become The Best Treatment Option?

      in Chat  12 upvotes 3 years ago
      The conversation discusses GT20029 as a potential hair loss treatment that could act like a cure by targeting androgen receptors in scalp hair follicles. Specific treatments mentioned include GT20029, with a user expressing hope that it could make male pattern baldness obsolete.

      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 2 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community Hair loss - Blood work (High DHEAS)

      in Research/Science  7 upvotes 4 years ago
      A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.
      Help: Digital Perm while Thinning Hairline

      community Help: Digital Perm while Thinning Hairline

      in Basic Questions  142 upvotes 1 week ago
      A 20-year-old male experiencing hair loss is using finasteride for 8 months and is considering a digital perm but is concerned about potential hair damage, especially at the thinning hairline. Advice given includes continuing finasteride, using gentle hair products, and possibly trying topical minoxidil or CBD cream for scalp care.

      community Has anyone seen the data on this 539% boost breakthrough?

      in Technology  868 upvotes 1 month ago
      Topical Clascoterone showed a 539% improvement in hair count compared to placebo, but its effectiveness and safety are debated. Users compared it to minoxidil and finasteride, with mixed opinions on its potential release in 2026 or 2027.

      community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?

      in Update  1 upvotes 1 year ago
      The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

      community Duoxidil / Dutasteride/ Minoxidil

      in Minoxidil  83 upvotes 1 year ago
      The conversation discusses a user's positive experience with hair loss treatments, including Duoxidil, oral Dutasteride, oral Minoxidil, and biotin, noting no side effects and effective results. The user plans to start a new cycle of Dutasteride and PRP sessions.

      community Anyone knows if koshine kx-826 has propylene glicol?

      in Product 6 months ago
      Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.

      community Is injections with dermapen possible?

      in Microneedling  8 upvotes 1 year ago
      A user is considering using a dermapen with liquid solutions like minoxidil for hair loss as a cost-effective alternative to mesotherapy. They seek advice on the effectiveness and experience with such devices.