Hairloss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
Finasteride and dutasteride can prevent hairloss if used early, but they may cause side effects. Many men shave their heads because they are unaware of these treatments or avoid them due to side effects or cost.
Switching from finasteride to dutasteride for hairloss yields mixed results, with some users experiencing improvements and others facing worsening conditions or side effects like shedding. Patience is advised as dutasteride may take longer to show results, and combining treatments is suggested by some users.
Stopping minoxidil and finasteride for three months caused significant hairloss. The user resumed treatment with 2.5mg oral minoxidil and 0.6mg finasteride and plans to update on progress in three months.
Scalp biopsies are crucial for diagnosing hairloss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hairloss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.
Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
Pyrilutimide, a treatment for hairloss; it's effectiveness compared to other treatments such as Finasteride and RU58841; and some users’ experiences with the treatment.
A 21 year old who has been taking various treatments for hairloss such as dutasteride, RU58841, minoxidil and finasteride with no results. Other users share their experiences of dealing with hairloss at an early age and offer advice on how to cope.
Creatine may cause hairloss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.
Homelessness is humorously proposed as a solution to hairloss due to less grooming and stress. Treatments like Minoxidil and Finasteride are discussed, with genetics and lifestyle also considered important factors.
PP405 is a promising hair growth stimulant but not a cure for advanced hairloss, as it may only help dormant follicles. Treatments like Minoxidil, Finasteride, and Dutasteride are discussed, with emphasis on early intervention for effectiveness.
Why the top of the head is affected by hairloss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.
An 18-year-old is experiencing worsening hairloss, feeling isolated, and considering treatments like Minoxidil and finasteride. Others suggest seeing a dermatologist to determine the cause and potential treatments.
A 21-year-old male managed to control his hairloss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hairloss, with some reporting negative effects and others seeing no change or defending its benefits.
Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hairloss, and the potential financial motivations of companies not wanting to find a cure.
A user experienced a hard lump under their nipple and increased hairloss after four months of finasteride. They are concerned about the lump and plan to stop the treatment.
User GreatCanuck experienced hair regrowth after using finasteride for a year, reducing anxiety about hairloss. Others in the conversation shared similar positive experiences and discussed family members using the treatment.
Gut microbiota significantly influences androgen metabolism, impacting hairlosstreatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
The conversation discusses the use of topical minoxidil and finasteride for hairloss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.
A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hairloss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.
A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hairlosstreatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.
Federal funding cuts have delayed PP405 research, affecting hairlosstreatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.
The conversation discusses how many male models and celebrities likely use finasteride to prevent hairloss, with some expressing surprise that it's not just good genetics keeping their hair intact. Specific treatments mentioned include finasteride and, in one query, minoxidil.
Oral biotin combined with topical minoxidil may increase hair growth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.
The conversation discusses skepticism about the effectiveness of scalp tension theory and scalp massagers for hair regrowth, contrasting it with treatments like finasteride and minoxidil, which have more user-reported results. Participants question the belief in scalp tension theory, suggesting it may be a marketing tactic, while others argue for a multifactorial approach to hairloss.
People are eagerly awaiting the release of PP405, a new hairlosstreatment. Some are using minoxidil and finasteride in the meantime, but there are concerns about scams and unverified products.