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      community I hope ET-02 or PP405 will be released in the next 4-5 years

      in Product  15 upvotes 10 months ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community Oral min 2.5mg / oral fin 1mg / 3.5 months - 25M progress

      in Progress Pictures  167 upvotes 10 months ago
      A 25-year-old shared progress on hair growth using oral minoxidil 2.5mg, oral finasteride 1mg, and dermarolling over 3.5 months, noting improvements and encouraging others to persist with treatments. Other users discussed their experiences with similar treatments, including topical minoxidil, ketoconazole shampoo, and tretinoin cream, with varying results and side effects.

      community the "its so over / we're so back" pendulum

      in Chat  180 upvotes 1 year ago
      People with hair loss experience emotional struggles and body dysmorphia. Treatments like minoxidil, finasteride, and dutasteride are used, but results vary and can take time.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  14 upvotes 3 years ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

      community 3 months on minoxidil and microneedling alone

      in Progress Pictures  634 upvotes 3 years ago
      This conversation was about a user's progress pictures from using minoxidil and microneedling to treat hair loss. Other users suggested finasteride as an additional treatment, while cautioning that the drug could have permanent side effects.

      community Minoxidil can prevent hair follicle miniaturization!?

      in Minoxidil  5 upvotes 4 years ago
      Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hair loss; hair loss could be due to multiple factors, including autoimmune conditions.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  12 upvotes 5 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Natural Remedies: Polyphenols and Hair Loss

       20 upvotes 6 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Early Signs - Notes for diffuse thinners

      in Treatment  12 upvotes 2 months ago
      Diffuse thinning is often due to androgenetic alopecia, and DHT blockers like finasteride are recommended. Treatments mentioned include minoxidil, finasteride, dutasteride, and RU58841, with emphasis on starting early and using a holistic approach.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  43 upvotes 6 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Thoughts on the future of pp405?

      in Research/Science  42 upvotes 4 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 7 months ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community Regression? Has anyone experienced this?

      in Progress Pictures  46 upvotes 10 months ago
      The user is experiencing increased hair shedding and is concerned about regression despite consistent use of finasteride, minoxidil, and other treatments. The consensus is that this is likely a temporary shedding phase, and adjustments to the dermarolling frequency are suggested.

      community Did UCLA Just Cure Baldness? Check this Out!

      in Research/Science  968 upvotes 1 year ago
      UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  101 upvotes 2 years ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community TDM-105795 phase 2 results are in!

      in Research/Science  29 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 2 years ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.