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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Looking for Latanoprost sources EU

      in Product  2 upvotes 2 years ago
      The user has been using MinoxidilMax Latanoprost 0.01% and noticed an increase in hair density after years of stability on finasteride and minoxidil. They are seeking help to find a higher dosage of Latanoprost or a reliable source to purchase the powder to make their own, without a prescription or high cost.

      community HMI-115 question about potential earliest access

      in Research/Science  8 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community Female androgenetic alopecia (w/ PCOS) starting treatment

      in Female  5 upvotes 1 year ago
      A female with PCOS and androgenetic alopecia is starting treatment with oral Minoxidil, topical Minoxidil 5% with finasteride, and plans to add mesotherapy. She previously tried anti-androgenic contraceptive pills but couldn't tolerate them and is using Myo Inositol for weight management.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  1 upvotes 2 weeks ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 9 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community 30 M diffuse shining/bolding crown - stack

      in Treatment  2 upvotes 1 year ago
      A 30-year-old with diffuse thinning and a balding crown is using a treatment regimen of a 2-in-1 pill containing finasteride, minoxidil, and biotin, along with various supplements. After two weeks, no side effects have been experienced, and updates with pictures will be posted monthly.

      community Liquid minoxidil + pyrilutamide

      in Treatment  17 upvotes 3 years ago
      Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  14 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Solo use of Pyrilutamide: UPDATE

      in Update  45 upvotes 3 years ago
      A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

      community Oral fin/min/biotin Stack 2 month progress pics

      in Progress Pictures  15 upvotes 2 months ago
      The conversation is about a user's progress with an oral treatment for hair loss using a stack of finasteride, minoxidil, and biotin over two months, noting stabilization after an initial shed. The user mentions using Hims Chews, which are effective but costly, and another user comments that biotin is ineffective.

      community folligenz liposomal minoxidil sulfate

      in Chat 2 weeks ago
      Folligenz liposomal minoxidil sulfate is being discussed for its effectiveness and cost, with users comparing it to regular minoxidil and tretinoin. One user found no difference with the 10% version and noted that a lower tretinoin percentage reduced side effects like skin peeling.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 10 months ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community Tropoelastin injections + verteporfin?

      in Research/Science  12 upvotes 3 years ago
      The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

      community Crown recovery - almost fully back. November 2024 to now

      in Progress Pictures  1197 upvotes 1 year ago
      A 29-year-old shared their crown hair recovery using a daily liposomal topical solution of finasteride and minoxidil, low-level light therapy, and specific vitamins, noting significant improvement without side effects. They experienced issues with oral finasteride previously but not with the topical treatment.

      community Before HT and after HT (10 months)

      in Transplants  22 upvotes 1 year ago
      The user stopped using finasteride and minoxidil after a hair transplant, now only using coconut oil and serum, and is concerned about potential hair loss. Others advise continuing finasteride to prevent future hair loss, despite the user's doctor suggesting it's unnecessary.

      community Dutasteride and elevated (LDL) cholesterol

      in Finasteride/Dutasteride  1 upvotes 11 months ago
      The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.