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      community What ever happened to pyrilutamide?

      in Technology  49 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community The Hormonal Profile of MPB/AGA

      in Research/Science  9 upvotes 4 years ago
      Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Correct way to microneedling, with existent hair

      in Microneedling  12 upvotes 1 year ago
      The conversation discusses the correct method of microneedling for hair loss, questioning whether it should be done on areas with long hair without risking hair damage, and if it's necessary for improving blood flow to existing hair. No specific treatments were mentioned.

      community Dutasteride Mesotherapy Works – Just 1 month results

      in Progress Pictures  110 upvotes 3 years ago
      The effectiveness of using dutasteride mesotherapy as a hair loss treatment, with other protocols such as microneedling, vitamin D and B12, zinc, and biotin. The user's results were positive after 4-6 months without any serious side effects.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community Anyone had anemia + AGA/thinning ?

      in Treatment  4 upvotes 11 months ago
      OP experienced significant hair regrowth after recovering from iron deficiency anemia and starting minoxidil. They suspect anemia contributed more to their hair loss than androgenetic alopecia (AGA).

      community Pyrilutamide from Hairlisciously? Other suppliers?

      in Treatment  8 upvotes 3 years ago
      The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

      community Connection between finasteride and nafld?

      in Research/Science  4 upvotes 1 year ago
      Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.
      18M: Thinning and Hair Loss at Temples - Advice Needed

      community 18M: Thinning and Hair Loss at Temples - Advice Needed

      in General  51 upvotes 9 months ago
      The user is experiencing hair thinning and loss at the temples, likely due to androgenetic alopecia. Suggested treatments include finasteride and minoxidil to slow hair loss and promote regrowth, with buzzing hair short as a styling option.

      community Anyone tried topical adenosine?

      in Product  4 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community Why does MPB only affect the scalp

      in Research/Science  14 upvotes 1 year ago
      Male pattern baldness (MPB) may be influenced by androgen receptors in scalp hair follicles and potentially poor blood flow. Transplanted hair is not immune to DHT, and factors like inflammation and scalp tension might also contribute to hair loss.

      community Sweet Lord my DHT itch is finally gone

      in Chat  49 upvotes 2 years ago
      Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  14 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 11 months ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Wimpole Clinic 1850 grafts (23yo) Dr Malkani

      in Progress Pictures  123 upvotes 1 year ago
      A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.

      community A rare case? Or a blind spot? Hair loss caused by low T + e2

      in Chat  10 upvotes 10 months ago
      Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.

      community Using the nuclear stack and still losing hair... Is this the end for my hair?

      in Update  4 upvotes 3 years ago
      The user is experiencing ongoing hair loss despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, cyproterone acetate, transdermal estradiol, and topical bicalutamide. They suspect cyproterone acetate may be worsening their hair loss and are considering switching to injection monotherapy.

      community If after 3 years nothing works should i get scalp biopsy

      in Treatment  7 upvotes 1 year ago
      The user has tried various treatments like Dutasteride, RU58841, Minoxidil, Finasteride, Spironolactone, Pyrilutamide, and Ketoconazole for hair loss without success and is considering a scalp biopsy to diagnose another condition. Others suggest consulting a dermatologist and possibly getting a biopsy, as the issue might not be typical male pattern baldness.

      community NW5 advice current treatments AGA

      in Treatment  5 upvotes 4 years ago
      Minoxidil, PRP, low-level light therapy, stem cell therapy, mesotherapy, Acell, and microneedling are discussed as treatments for thickening fine hairs in NW5 hair loss sufferers. A hair transplant may be necessary for significant improvement.

      community There is news from pyrilutamide?

      in Product  32 upvotes 2 years ago
      The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.