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      community Topilutamide (fluridil) raw active?

      in Research/Science  7 upvotes 5 years ago
      Topilutamide is a potential hair loss treatment between Clascoterone and RU58841. Users discuss finding Topilutamide powder and its possible benefits for those who can't afford or tolerate other treatments.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Is it possible/legal to buy clascoterone in Spain?

      in Treatment  2 upvotes 8 months ago
      The user has tried various hair loss treatments, including topilutamide, alfatradiol, pyrilutamide, and topical spironolactone, but experienced headaches. They are inquiring about the availability and legality of clascoterone in Spain.

      community DHT itch, dandruff and sebum plugs.

      in Hair Systems  1 upvotes 4 years ago
      The conversation discusses hair loss treatments, focusing on reducing scalp itching and dandruff using natural shampoos, witch hazel, and apple cider vinegar. The user also mentions using finasteride and observing potential regrowth, though it's difficult to confirm.

      community Hair Lotion Suggestion Needed!

      in Product  3 upvotes 7 months ago
      A user is seeking suggestions for a custom hair lotion mix containing minoxidil, finasteride, caffeine, niacinamide, and biotin. Another user suggests adding tretinoin, topical valproate, and bimatoprost.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  185 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community Minoxidil+ Spray by keep does it contain propylene glycol?

      in Minoxidil  1 upvotes 1 year ago
      The user is using Dutasteride and oral Minoxidil for hair regrowth and is considering adding topical Minoxidil but is allergic to propylene glycol, which is present in the product they found. They need a solution with tretinoin that does not contain propylene glycol.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 5 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Anyone else experiencing scalp inflammation? Get in here!

       6 upvotes 7 years ago
      A user found that taking Zyrtec (Cetirizine) and Advil helped reduce their scalp inflammation and pain, potentially creating a better environment for hair growth. They have not used any other medication for hair loss or scalp issues.

      community Extremely potent catalyst for Minoxidil

      in Minoxidil  6 upvotes 6 years ago
      Using Megatek with minoxidil significantly increases hair growth, especially vellus hairs, but is less effective alone. Biotin and ketoconazole shampoo are also used to support hair health.
      Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      community Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      in General  119 upvotes 3 months ago
      A user is considering switching from a 5% minoxidil spray to a minoxidil cream for easier application and less greasiness. They are inquiring about the Hair Repair Clinic 5% minoxidil cream, which includes optional tretinoin and other ingredients like isopropyl myristate and beeswax.

      community The future of hair loss drugs.

      in Research/Science  32 upvotes 2 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community It's always the Mice that gets to grow back hair.

      in Research/Science  431 upvotes 5 months ago
      Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

      community Hair Repair Clinic - are they legit?

      in Treatment  1 upvotes 1 month ago
      The conversation discusses the legitimacy of Hair Repair Clinic's topical products and the use of ethanol/water solution instead of trichosol for finasteride. The user prefers ethanol for faster drying and less odor.

      community Is this hierarchy of topical anti androgens accurate?

      in Ketoconazole  6 upvotes 3 years ago
      User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

      community Anyone have experience with 82M?

      in Question 8 years ago
      A user with diffuse thinning, currently using finasteride, biotin, minoxidil, and nizoral shampoo, is considering a topical solution called "82M" but is skeptical due to its high cost and lack of supporting research. They seek others' experiences with "82M."

      community Minoxidil and concern about cats

      in Minoxidil  5 upvotes 9 months ago
      Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Breezula CB-03-01

      in Treatment  10 upvotes 6 years ago
      The conversation is about a potential new hair loss treatment called Breezula CB-03-01. Users are discussing updates on its development and sharing personal experiences with making or using it.