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      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 3 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community Is it normal that fin tingles in the mouth?

      in Finasteride  59 upvotes 1 year ago
      A user experienced a tingling sensation in their mouth after taking a cut finasteride pill, possibly due to inactive ingredients like mannitol or sodium lauryl sulfate. Tingling is not a common side effect or typical allergy sign, but monitoring for unusual reactions is advised.

      community So is this the actual trial results for pp405?????

      in Research/Science  92 upvotes 2 months ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

      community M30/India : Tried GHK-Cu for Hairline. Sharing results

      in Progress Pictures  45 upvotes 1 month ago
      A user experienced side effects from finasteride and switched to using GHK-Cu for hairline improvement, noticing some positive changes after three months. They used a 2mg daily dose via subcutaneous injections and reported increased hair density and baby hairs, though results were not dramatic.

      community Put P5P in my shampoo, reduced itch a lot!

      in Chat  4 upvotes 3 years ago
      The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.

      community Let's talk about Tsuji and Shiseido

       5 upvotes 7 years ago
      The conversation discusses hair loss treatments, focusing on Tsuji's hair cloning and Shiseido's RCH-01, with skepticism about their effectiveness on humans. It compares these to PRP, noting PRP's higher efficacy in studies.

      community Min/Fin topical prescription also contains Latanoprost?

      in Treatment  3 upvotes 1 year ago
      A user discusses a topical prescription for hair regrowth containing Minoxidil, Finasteride, and Latanoprost, noting Latanoprost's side effect of promoting eyelash and eyebrow growth. Others share experiences and information about Latanoprost, highlighting its origins as a glaucoma drug and potential side effects.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 11 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community New Hair Loss Treatment: Adipose Derived Secretomes

      in Research/Science  17 upvotes 1 year ago
      Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

      community Minoxidil, Fin and Cetirizine.

      in Treatment  6 upvotes 3 years ago
      The user started a hair care routine using 0.5mg finasteride daily, 2ml of 5% minoxidil, and 4.5mg of cetirizine topically to address hair loss. They plan to provide updates and are also interested in cetirizine's potential to reduce scalp itching and redness due to its anti-inflammatory properties.

      community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

      in Treatment  22 upvotes 2 years ago
      Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 8 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

      in Research/Science  57 upvotes 11 months ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community Potential pp405 info next week at masters of athetics

      in Treatment  59 upvotes 6 months ago
      Discussion on hair loss treatments, focusing on pp405, with skepticism about its effectiveness and concerns about its association with the cosmetic industry. Users also mention treatments like Minoxidil and Finasteride.

      community Anyone have experience with latanoprost topical?

      in Treatment  1 upvotes 2 years ago
      The post discusses the use of latanoprost foam for hair growth, with the user expressing concerns about its efficiency and safety. The user is currently using topical dutasteride, which maintains their hair but doesn't promote regrowth, and is seeking a product that doesn't affect hormone levels.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community 3 month progress on min + fin capsule

      in Is this regrowth?  400 upvotes 1 year ago
      The user experienced significant hair regrowth in three months using a capsule containing minoxidil and finasteride. They reported no major side effects and plan to continue the treatment until their late 20s.

      community Creating the Holy Grail Hair Loss Topical

       1 upvotes 6 years ago
      The conversation is about creating a natural hair loss topical using ingredients like cetirizine, Zinc Sulphate Heptahydrate, Safflower Extract, Ricinoleic Acid, and others. The user is seeking input and collaboration on this topical formula.