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      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 8 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community 2 months in my regrowth journey

      in Progress Pictures  13 upvotes 8 months ago
      The user is using finasteride, topical minoxidil, derma rolling, ketoconazole shampoo, and multivitamins for hair regrowth. They also drink topical minoxidil due to the unavailability of oral minoxidil, despite concerns from others about safety.

      community Is microneedling still worth it if I’m on oral minoxidil?

      in Microneedling  21 upvotes 8 months ago
      Microneedling may still be beneficial for those on oral minoxidil due to its effects on tissue repair and blood flow, not just absorption. Some users report mixed results, and the effectiveness of combining microneedling with oral treatments remains debated.

      community Topical dutasteride significantly outperforms oral finasteride

      in Research/Science  65 upvotes 8 months ago
      Topical dutasteride 0.05% is reported to outperform oral finasteride with minimal side effects, but concerns about study bias exist due to company funding. Some users report mixed results with topical dutasteride, noting issues with skin penetration and systemic absorption.

      community Wrap it up everyone. CB-03-01 is another failed treatment

      in Treatment  80 upvotes 8 months ago
      CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

      community Justin Trudeau really is one lucky guy

      in Satire  233 upvotes 8 months ago
      Justin Trudeau's full head of hair at 53 is humorously attributed to unpredictable genetics and possible use of finasteride. The conversation jokes about a resemblance to Fidel Castro, suggesting genetic luck or treatment use.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 8 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community almost 4 years of my hair regrowth journey

      in Progress Pictures  42 upvotes 8 months ago
      The user shared their 4-year hair regrowth journey using finasteride, minoxidil, RU58841, microneedling, and Nizoral shampoo. They plan to adjust their RU58841 dosage and are considering a hair transplant if current methods don't yield desired results.

      community Yes your lifestyle and diet has its role in hair loss.

      in Chat  296 upvotes 9 months ago
      Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

      community What product does David Dobrik use

      in Chat  336 upvotes 9 months ago
      David Dobrik uses Minoxidil and possibly Finasteride for hair loss but applies them incorrectly. Users suggest he consider surgery due to his financial capability.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  43 upvotes 10 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Pyrilutamide 4 Month Journey with progress Pics..!!!

      in Progress Pictures  21 upvotes 10 months ago
      The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

      community 6-Month Progress Update: Fin & Min

      in Is this regrowth?  65 upvotes 10 months ago
      A 31-year-old experienced hair regrowth using a daily regimen of 5% minoxidil spray and 1mg oral finasteride over six months, with no side effects. The user noticed slow but positive progress, especially in the temple area, and plans to continue the treatment as advised by their doctor.

      community A 100-day transformation of shedding

      in Progress Pictures  8 upvotes 10 months ago
      OP shared a 100-day progress on reducing hair shedding using Minoxidil and Dorpang scalp serum, noting healthier hair growth. Other users discussed their own treatments, including Minoxidil, ketoconazole, saw palmetto, and pumpkin seed oil, with some considering finasteride if needed.

      community 1 year 3 months on Finasteride - Still improving!

      in Progress Pictures  362 upvotes 10 months ago
      A user in their early twenties shared progress after 1 year and 3 months on 1mg daily oral finasteride, reporting no side effects and improvements despite initial shedding. They emphasized the importance of early intervention and noted that results come in waves, with shedding followed by regrowth.

      community Summary of future treatments from 2020

      in Chat  53 upvotes 10 months ago
      Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

      community Let’s get PP405 trending on Twitter!

      in Chat  69 upvotes 11 months ago
      People are excited about a new hair loss treatment, PP405, and some suggest using Twitter to increase its visibility. Current treatments mentioned include finasteride, minoxidil, and dutasteride, but skepticism remains about the effectiveness of new treatments.

      community What do you think about this study?

      in Product  112 upvotes 11 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about the effectiveness and availability of future solutions. Current treatments like minoxidil, finasteride, and hair transplants are mentioned as reliable options.

      community Sharing My Routine – Hope It Helps Someone Else Too

      in Progress Pictures  638 upvotes 11 months ago
      The conversation discusses a user's positive experience with a hair loss treatment routine involving dutasteride, oral minoxidil, and Nourkrin Man, with no side effects reported. Other users share their experiences with similar treatments, discussing side effects like heart palpitations and depression, and offer advice on obtaining prescriptions affordably.

      community risks with finasteride and dutasteride

      in Research/Science  141 upvotes 11 months ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community Mix tretinoin into minoxidil bottle

      in Treatment  1 upvotes 11 months ago
      Mixing tretinoin with minoxidil for hair loss treatment. Some users prefer separate application or professional compounding due to potential solubility issues.

      community On the big 6 but very slow , needs acceleration

      in Is this regrowth?  30 upvotes 11 months ago
      The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

      community Dutasteride Users, do you Still Take Creatine?

      in Finasteride/Dutasteride  11 upvotes 11 months ago
      The conversation discusses the potential impact of creatine on hair loss, with some users sharing personal experiences of increased shedding while others argue there's no scientific evidence linking creatine to hair loss. The original poster switched from finasteride to dutasteride and is considering resuming creatine after monitoring its effects on hair loss.

      community Getting PP405. Now…. or as soon as possible

      in Research/Science  145 upvotes 11 months ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.