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Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.

The user experienced hair regrowth using dutasteride daily, microneedling weekly, and Nizoral shampoo, after stopping minoxidil due to side effects. They also use a mix of pumpkin seed, rosemary, and peppermint oil, and are considering RU58841 for more temple area thickness.

PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

The user is experiencing increased hair thinning and shedding despite using oral dutasteride, oral minoxidil, topical dutasteride, and ketoconazole shampoo. Many recommend considering a hair transplant or embracing baldness, as current treatments seem ineffective.

The user is using minoxidil, topical finasteride, Nizoral shampoo, and a dermaroller for hair regrowth but is experiencing changes in sexual function. They are concerned about whether these changes are due to the treatment and are seeking advice on continuing hair growth without affecting sexuality.

A 31-year-old man using finasteride for a year is considering adding oral minoxidil or switching to topical minoxidil to address diffuse thinning, while also using a scalp massager and ketoconazole shampoo. Concerns include cardiovascular side effects, pet safety with topical minoxidil, and cost of telehealth services.

The user experienced significant hair regrowth using oral and topical minoxidil, dutasteride, and microneedling, with natural hair returning despite previous baldness and transplants. The treatment appears effective, as hair has darkened and increased in length.

A user is experiencing worsening hair loss despite using dutasteride, oral minoxidil, ketoconazole, and dermarolling. They are advised to reduce dermarolling frequency and depth to avoid damaging hair follicles.

A user shares their hair loss treatment regimen, which includes oral finasteride, oral and topical minoxidil, RU58841, LLLT cap, microneedling, ketoconazole shampoo, biotin, vitamin D3, NAC supplement, MK677, collagen, and other hair care products. They seek opinions on its effectiveness.

A Phase II clinical trial for TDM-105795 has started recruiting in the US, and it might be a promising treatment for hair loss. Many hair loss drugs, including this one, originate from China.

A user experienced rapid hair loss and successfully regrew hair using minoxidil daily and finasteride 0.5mg every other day, along with lifestyle changes. They reported significant improvement after initial setbacks and emphasized the importance of starting treatment early.

The user has been treating hair loss for two months using 5% minoxidil, 0.25% topical finasteride, ketoconazole 1% shampoo, and microneedling. They report visible progress and plan to continue the treatment.

The conversation humorously discusses the unfairness of hair loss, highlighting various treatments like finasteride, minoxidil, red light therapy, and experimental drugs, while contrasting with people who have great hair despite unhealthy lifestyles. The original poster mentions experiencing side effects from switching to oral finasteride.

The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.

The user experienced hair thinning and used microneedling, DHT blocking shampoo, and Biotin DHT blocking oil to address it, avoiding finasteride and minoxidil unless necessary later. They reported mild improvement but received mixed feedback, with some suggesting other conditions or treatments like ciclopirox shampoo.

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

The user plans to use a "nuclear protocol" for hair improvement, including topical minoxidil 12.5%, topical finasteride 0.1%, and tretinoin 0.05%, with microneedling once a week. They have seen improvements with minoxidil and are seeking opinions on their approach to achieve thicker hair.

Clascoterone is seen as a promising topical treatment for hair loss, similar to finasteride but without side effects, though concerns exist about its long-term effectiveness. Other treatments discussed include topical minoxidil, ketoconazole, microneedling, and oral options like dutasteride and minoxidil.

The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

The user "_Mad_Jack_" shared their progress pictures of using topical finasteride and minoxidil for 11 months. They experienced good hair retention and increased overall hair count, but no regrowth of the hairline. They are considering switching to oral finasteride and microneedling for better results. Testicular pain was a side effect experienced during the treatment. Another user mentioned getting a hair transplant to cover their crown.

The conversation discusses a hair loss treatment regimen involving high doses of dutasteride, finasteride, and minoxidil, with concerns about safety and potential side effects. Users advise against the excessive use of these medications, suggesting more moderate approaches and consulting a doctor.

The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

A 31-year-old experiencing rapid hair loss is considering whether to shave their head or use treatments. They were prescribed B12, topical finasteride 0.1%, and minoxidil 10% but are unsure about the correct dosage and potential side effects.

A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.

The user experienced side effects like watery semen, erection problems, and decreased libido from finasteride, which resolved after stopping it. They are considering dutasteride mesotherapy as an alternative, as advised by their dermatologist, and are concerned about potential side effects.

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.