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      community Shaved my (transplanted) hair during quarantine

      in Shaved/buzzed  102 upvotes 5 years ago
      A user shaved their transplanted hair during quarantine and shared positive results after one year, using Minoxidil 5%. They had 1,500 hairs transplanted via the DHI method with no visible scarring.

      community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )

      in Treatment  3 upvotes 6 years ago
      The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.

      community PP405 - hair stem cell stimulation

      in Research/Science  51 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community RU58841 in Pumpkin Seed Oil (PSO)

      in Treatment  4 upvotes 1 year ago
      A user is seeing good results with RU58841 for hair loss, noting reduced shedding and thicker hair. They plan to use pumpkin seed oil as a solvent to avoid water content, which they believe reduces the effectiveness of anti-androgens.

      community What the hell happened to Breezula?

      in Research/Science  15 upvotes 8 months ago
      Breezula (clascoterone) Phase 3 hair loss trial results are delayed, with no official updates yet. The acne version is approved, but hair loss results are still pending.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community Can we get a reality check on PP405?

      in Research/Science  83 upvotes 5 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community Hairloss and dandruff.. potential sebderm inflammation?

      in Research/Science  1 upvotes 1 year ago
      A 21-year-old is experiencing aggressive hair loss and dandruff, possibly due to seborrheic dermatitis, and is using pumpkin seed oil, scalp massages, and anti-dandruff shampoo as treatments. They are hesitant to use prescribed Finasteride and Minoxidil and have noticed some improvement after stopping Serenoa capsules.

      community Finally Shaved It

      in Shaved/buzzed  102 upvotes 5 years ago
      User tired of receding hairline and maintenance, shaved head. Others compliment shaved look and beard genetics.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  14 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  11 upvotes 2 years ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community Tressless When They See Verteporfin Results

      in Transplants  183 upvotes 2 years ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community DIY PRP Scalp Injections - wish me luck!

      in Treatment  41 upvotes 5 years ago
      A user shared their experience with DIY PRP scalp injections for hair regrowth, using an EZ Injector and other at-home equipment. Another user reported success with at-home PRP treatments for 1.5 years, noting thicker hair and a stable hairline.

      community Potential Cure?! Verteporfin- unlimited HT

      in Research/Science  44 upvotes 2 years ago
      The conversation discusses verteporfin as a potential treatment for hair regeneration, which could lead to unlimited hair transplants by healing the donor area. Some users are considering using verteporfin now, while others are hopeful it will be available for future hair transplants.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 6 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community $120 million Series B funding to Pelsge

      in Research/Science  56 upvotes 5 months ago
      Pelage Pharmaceuticals received $120 million in Series B funding for hair loss treatment development. The conversation expresses excitement and anticipation for the release and effectiveness of the treatment.

      community Why Didn't the Pumkin Seed Oil Study Get More Attention?

      in Question  67 upvotes 6 years ago
      Pumpkin seed oil showed a 40% increase in hair count, but its effectiveness is questioned due to other ingredients in the supplement. Users discuss its potential compared to finasteride, with some expressing skepticism and others showing interest.

      community Exosomes injections

       6 upvotes 6 years ago
      User tried finasteride and minoxidil for hair loss, now considering exosomes injections. Will update on results after appointment.