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      community How’s RCH-01 doing?

      in Treatment  6 upvotes 6 years ago
      RCH-01's progress is uncertain, and there's skepticism about its effectiveness. Users are losing hope in this treatment.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community The urge to buy Clascoterone 5% solution

      in Research/Science  11 upvotes 6 months ago
      Clascoterone 5% solution is not yet commercially available, with only the 1% solution currently sold for acne. Users discuss the potential of Clascoterone as a hair loss treatment, comparing it to other anti-androgens like RU58841 and Eucapil.

      community Alfatradiol 0.1% anyone know a source?

      in Treatment  3 upvotes 1 year ago
      The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

      community antihistamine for scalp inflammation??

      in Chat  5 upvotes 1 year ago
      Cetirizine 10mg daily reduced hair shedding by 50% and lessened scalp itchiness. The user is considering long-term use for scalp inflammation and hair loss.

      community My kotoconazole shampoo contain this

      in Ketoconazole 2 months ago
      The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community questions for the pyrilutamide users here

      in Treatment  7 upvotes 3 years ago
      The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.

      community Do any shampoos contain Piroctone Olamine in the US

      in Product  3 upvotes 1 year ago
      The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

      community Pyrilutamide (KX-826) vs CB-03-01 which one do you think is better?

      in Product  8 upvotes 3 years ago
      The conversation is about comparing hair loss treatments Pyrilutamide (KX-826) and CB-03-01, discussing their cost, side effects, and effectiveness. The user questions whether to try CB-03-01, which is more expensive and potentially less effective, or switch to the cheaper and possibly better Pyrilutamide.

      community 0.25 alfatradiol or 0.5 Pyrulitamide ?

      in Product  4 upvotes 7 months ago
      The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

      community pyrilutamide any results so far?

      in Treatment  44 upvotes 3 years ago
      The hair loss treatment Pyrilutamide and whether it has had any results for users. Martinsahara is planning to buy some soon.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  184 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community What is next for pp405 in phase 2b?

      in Research/Science  16 upvotes 11 months ago
      PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.

      community The best vehicle/carrier for RU58841

      in Treatment  2 upvotes 2 years ago
      The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.