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GlossaryChlorpheniramine

antihistamine used to relieve allergy symptoms like sneezing and itching

Chlorpheniramine, also known as Chlorpheniramine Maleate or by brand names like Chlor-Trimeton, is an antihistamine used to relieve allergy symptoms such as runny nose, itching, and sneezing. It works by blocking histamine, a substance in the body that causes allergic reactions.

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community Currently participating in the Extended Phase III clinical trial of Pyrilutamid in China

in Technology 81 upvotes 2 years ago

A user from China is participating in a clinical trial for Pyrilutamid, a potential hair loss treatment originally developed for prostate cancer. They've experienced no side effects except initial scalp itchiness, and will share results after the year-long trial.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 2 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community antihistamine for scalp inflammation??

in Chat 5 upvotes 1 year ago

Cetirizine 10mg daily reduced hair shedding by 50% and lessened scalp itchiness. The user is considering long-term use for scalp inflammation and hair loss.

community Antihistamines interaction with Finasteride.

in Update 2 upvotes 3 years ago

Stopping antihistamines may resolve neurological side effects when using finasteride. Users experienced muscle aches, headaches, and lethargy when combining the two.

community Fevipiprant 2019!

15 upvotes 9 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

in Research/Science 5 upvotes 2 years ago

The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

community Minoxidil, Fin and Cetirizine.

in Treatment 6 upvotes 3 years ago

The user started a hair care routine using 0.5mg finasteride daily, 2ml of 5% minoxidil, and 4.5mg of cetirizine topically to address hair loss. They plan to provide updates and are also interested in cetirizine's potential to reduce scalp itching and redness due to its anti-inflammatory properties.

community Pyrilutamide Phase 3 on its way

in Treatment 128 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community topical cetirizine to control scalp inflammation

in Treatment 5 upvotes 4 years ago

The user applies a topical solution containing minoxidil, finasteride, dutasteride, retinoic acid, and hydrocortisone to address scalp inflammation and is considering adding cetirizine to the mix. They are calculating the correct amount of cetirizine to add to their formula and have paused this approach to retry oral minoxidil.

community Will we be able to acquire pyrilutamide when it is on the market in China?

in Research/Science 9 upvotes 2 years ago

The conversation is about the possibility of obtaining Pyrilutamide, a hair loss treatment, once it becomes available in China, despite it not being approved by the US FDA yet. The user wants to use Pyrilutamide along with other treatments.

community Clascoterone is the way to go if you cannot use DHT blockers

in Chat 11 upvotes 1 month ago

Clascoterone is suggested as an alternative for those who experience side effects from finasteride and dutasteride. It is not widely available yet, but some users are obtaining it from compounding pharmacies or suppliers like Echemi.

community Group Buy for MR antagonist finerenone

in Product 11 upvotes 3 years ago

User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

community Do antihistamines help with hair loss

in Treatment 3 upvotes 9 months ago

A user experienced hair loss and texture changes, tried minoxidil and finasteride, and considered antihistamines like Cetirizine for potential histamine issues. They reported improved alertness but continued shedding.

community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

in Minoxidil 35 upvotes 3 years ago

The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

community 1% cetirizine (available in allergy medicines) for androgenetic alopecia

52 upvotes 6 years ago

The conversation discusses using 1% cetirizine, an antihistamine, as a potential treatment for androgenetic alopecia (hair loss). One user plans to try cetirizine instead of finasteride, while others are curious or skeptical about its effectiveness, discussing the role of inflammation in hair loss.

community EMA is re-examining Winlevi (clascoterone at lower concentration)

in Treatment 8 upvotes 11 months ago

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

community How to mix topical cetirizine with minoxidil?

in Treatment 1 upvotes 2 years ago

The conversation discusses combining topical cetirizine with minoxidil for hair loss treatment and inquires about the safety and absorption through the skin, as well as the possibility of adding melatonin.

community 15% discount various hair research products Chemyo.com

4 upvotes 9 years ago

A 15% discount is offered on hair research products like RU58841 and TEMPOL at Chemyo.com. The legality of selling these compounds is confirmed by the seller.

community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting

in Chat 30 upvotes 2 months ago

PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.

community Despite its straightforward mrchanism of action, it looks like pyrilitamide doesn't help regrow hair like finasteride does.

in Research/Science 7 upvotes 2 years ago

Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.

community Adding cetirizine tablet to minoxidil

in Treatment 3 upvotes 1 year ago

A user wants to add cetirizine tablets to their minoxidil bottle and asks how many 10mg tablets to crush for a 100ml bottle. They seek advice on the correct dosage.

community What’s the update on Pyrilutamide?

in Chat 12 upvotes 3 years ago

Pyrilutamide is seen as a last hope for those who can't take finasteride, with promising results reported. However, there's uncertainty about the quality and consistency of Pyrilutamide from black market sources.

community Where do I order pyrilutamide?

in Product 1 upvotes 3 years ago

Ordering pyrilutamide and minoxidilmax's quality. Seeking good source for purchase.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 43 upvotes 4 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community Low level chronic allergies and hair loss

in Research/Science 6 upvotes 2 years ago

Hair loss can be influenced by chronic low-level allergies, and treatments like fexofenadine or topical cetirizine may help with regrowth. The user avoids finasteride, dutasteride, and minoxidil, and has tried Regenera Activa and PRF sessions.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 1 year ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community Pyrilutamide cleared for phase 3 clinical trial in china

in Research/Science 28 upvotes 4 years ago

Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. Pyrilutamide cleared for phase 3 clinical trial in China.

community Allergan recruiting for Setipiprant trial in the US

13 upvotes 9 years ago

The conversation discusses a clinical trial for Setipiprant in the US, starting June 29th, with eligibility excluding recent users of minoxidil or finasteride. It encourages informed decision-making before signing up.

community CB-03-01 / Breezula Personal Results

in Treatment 17 upvotes 4 months ago

The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

community My experience with Pyrilutamide

in Update 3 upvotes 2 years ago

The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.