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      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 6 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community 5 year recovery while using steroids

      in Update  8 upvotes 11 months ago
      The user shared their 5-year hair recovery journey using finasteride, RU58841, dutasteride, minoxidil, and microneedling, noting mixed progress but overall improvement. They regret not starting treatment earlier and recently received positive health feedback from their doctor.

      community Result of my cortisol, prolactin, testosterone, ACTH blood test,

      in Update 5 months ago
      OP is using 5% minoxidil and a foligain supplement for hair loss, with blood test results showing high cortisol levels. OP is considering starting finasteride, while another user shares their experience with finasteride and hair loss challenges due to malabsorption issues.

      community It's always the Mice that gets to grow back hair.

      in Research/Science  431 upvotes 5 months ago
      Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

      community Progress at ~6 month mark dut/min

      in Progress Pictures  13 upvotes 1 month ago
      A user shared their 6-month progress using daily oral dutasteride and minoxidil, along with monthly mesotherapy including zinc, dutasteride, minoxidil, biotin, and panthenol, reporting no noticeable side effects. Encouragement was given to continue despite potential hair shedding.

      community Dermatologist recommends Evening-Primrose Oil

      in Treatment  2 upvotes 5 years ago
      A dermatologist recommended Evening-Primrose Oil, Biotin, Zinc, Vitamin D, and K to block DHT and address hair loss. The user is considering these alternatives to prescription drugs like finasteride.

      community Help labing up hair preservations

      in Research/Science 1 year ago
      The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.

      community Crazy question about sex sides

      in General  50 upvotes 10 months ago
      The conversation discusses using hormones like pregnenolone and tongkat ali to counteract sexual side effects from hair loss medications such as finasteride, dutasteride, ketoconazole, and minoxidil. The user stopped the other medications but continues using minoxidil while seeking advice on maintaining libido.

      community Personal results (1mg finasteride + 10.000mcg biotine) after almost 3 years. Not as impressive as some here, but maybe provides a more realistic view.

      in Progress Pictures  479 upvotes 4 years ago
      Jericho1017 shared their hair regrowth results after nearly 3 years using 1mg finasteride and 10,000mcg biotin daily, with noticeable improvement after 1.5 years and no significant side effects except for watery semen. Some users suggested adding minoxidil and microneedling to improve results, but Jericho1017 is currently content with their progress and not looking to add more treatments.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 1 month ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community 26M Baseline blood work done before Finasteride

      in Finasteride/Dutasteride  7 upvotes 4 years ago
      A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.

      community Clascoterone - what we have right now

      in Research/Science  19 upvotes 1 month ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 6 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community Anti androgen shed all over scalp

      in Treatment  3 upvotes 2 years ago
      The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.

      community Looking for feedback on my new regimen

       4 upvotes 8 years ago
      The conversation discusses a hair loss regimen involving finasteride, dutasteride, minoxidil, RU58841, and various supplements like biotin, omega-3, vitamin D3, zinc, and magnesium. The user also uses dermastamping and topicals like ketoconazole and diclofenac, with mixed opinions on zinc's effect on hair loss.

      community PSA: If you're prone to MPB dont take creatine

      in Update  106 upvotes 2 years ago
      Creatine might speed up hair loss in those prone to male pattern baldness, possibly due to increased DHT levels. Some users experience no issues when using creatine with treatments like finasteride, minoxidil, or dutasteride.