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300-330 / 1000+ resultscommunity The future of hair loss drugs.
Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.
community No-Finasteride Regime
User explores no-finasteride hair loss treatments, considering compounds like Minoxidil, Eucapil, Alfatradiol, Stemoxydeine, Azelaic Acid, Retinol, and Ketoconazole Shampoo. They ask about mixing compounds, application schedules, and potential side effects.
community Any treatment not nuking systemic DHT levels?
Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.
community Inhibition of collagen synthesis, oral versus topical minoxidil
community Dutasteride or treatment and TRT/PEDs
community Hormonal test advice to track post-treatment changes
Finasteride treatment is being considered, and it's advised to track DHT, testosterone, estradiol, and SHBG levels to monitor hormonal changes. These tests will help understand the treatment's impact.
community Topical Treatments and how would they work in a single compound
A topical treatment called 1961, containing multiple products, is discussed for its compatibility with finasteride. It is suggested that 1961 does not negatively affect finasteride's effectiveness and may even enhance its absorption.
community Why Is No One Talking About Chromosome 20?
Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.
community Don't use PP405 from everychem. it is likely fake.
PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.
community Study: Dutasteride Mesotherapy Accelerates Hair Loss in Female Patients with Metabolic Syndrome
Dutasteride mesotherapy in women with metabolic syndrome accelerated hair loss after initial regrowth, while women without metabolic syndrome saw continuous regrowth. The user with mild insulin resistance is hesitant to try topical dutasteride and seeks experiences from others with insulin resistance.
community Requesting Experiences: Topical Dutasteride - Liposomes vs. DMSO vs. Trichosol Results?
The conversation discusses experiences with topical dutasteride for hair loss, comparing formulations from FUEClinic, MinoxidilMax, and Strut. Users share their results and side effects, with some preferring topical over oral treatments to minimize systemic absorption.
community My blood work as a person with Ed suffer
High estradiol levels may contribute to erectile dysfunction (ED) and can be addressed with lifestyle changes or medication. It's important to consult a medical professional for treatment options.
community 15% discount various hair research products Chemyo.com
A 15% discount is offered on hair research products like RU58841 and TEMPOL at Chemyo.com. The legality of selling these compounds is confirmed by the seller.
community The ultimate regiment to reverse hairloss
The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.
community M-28, did a few hormone blood tests since I want a baseline before starting Fin. DhT high. But also Estradiol? Why?
community How to add stemoxydine into my routine
community Transition protocols from fin to dut
Transitioning from finasteride to dutasteride for hair loss, with suggestions to either slowly transition or frontload dutasteride. The user is also using minoxidil, nizoral, needling, and LLLT.
community Has anyone seen this study before? It claims that B6+Zinc can inhibit 5ar activity
The conversation discusses using B6 and Zinc to inhibit 5ar activity, similar to Fin and Dut. Minoxidil is mentioned as a supplementary treatment.
community Tried addressing DHT and regrowth, wanting to try additional path
The user is addressing hair loss with finasteride, dutasteride, oral and topical minoxidil, dermarolling, and shampoos. They are considering adding essential oils to improve circulation.
community When will Chinese manufacturers start producing Clascoterone 5%?
The conversation discusses the anticipation of Chinese manufacturers producing Clascoterone 5% before its full approval in 2027. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
community finasteride vs "natural" DHT blockers
The conversation discusses challenges in obtaining finasteride in the Netherlands and explores alternatives like natural DHT blockers and topical finasteride. Suggestions include consulting different doctors or dermatologists and considering cost-effective options like cutting higher-dose tablets.
community The story of RU58841/PSK3841
RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.
community This sub finasteride so much more complicated than it needs to be.
Take 1mg finasteride daily as the standard approach; adjust only if side effects occur. Many users experiment unnecessarily with doses and methods, complicating treatment.
community Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches
community Hormone level test results before starting topical liposomal finasteride: is my DHT level too high?
The conversation discusses using topical liposomal finasteride for hair loss, with concerns about high DHT levels. The user's DHT level is above the normal range, which may affect hair health.
community Compounded Dutasteride Absorption
Mixing Dutasteride with MCT oil may improve absorption due to its fat-soluble nature. Users suggest taking it with whole milk or using oil-based capsules for better effectiveness.
community Just checked my hormones before starting Fin
A user is considering starting finasteride for hair loss and shares their hormone levels, with others suggesting checking SHBG and discussing potential side effects. Some recommend starting with 0.5 mg finasteride, while others suggest considering dutasteride.
community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne
Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.
community Which is safest carrier for topical antiandrogens (finasteride/kx-826/ru/dutasteride)
The conversation is about finding a safe carrier for topical antiandrogens like finasteride, kx-826, RU58841, and dutasteride to minimize systemic absorption and side effects. The user experiences side effects from these treatments and is seeking advice on carriers that reduce these effects.