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      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  246 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  457 upvotes 7 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Finasteride with healthy hair at 20 good idea?

      in General  58 upvotes 8 months ago
      A 20-year-old with no signs of hair loss is considering finasteride or dutasteride due to family history of baldness. Advice given is to monitor hair and start treatment only if thinning occurs.

      community An *insane* RU58841 success story

      in Progress Pictures  99 upvotes 1 year ago
      RU58841, oral and topical minoxidil, finasteride, and ketoconazole shampoo led to significant hair regrowth, though some suspect a hair transplant. Concerns about RU58841's side effects, like anxiety and heart issues, were discussed.

      community KX-826 (Pyrilutamide) on Amazon

      in Treatment  9 upvotes 1 year ago
      The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

      community When is GT20029 going to come out?

      in Research/Science  40 upvotes 1 year ago
      The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community at what point does RCP no longer benefit?

      in Treatment  4 upvotes 1 year ago
      A user is using Minoxidil, finasteride, saw palmetto, and Minimalist RCP serum to address hair thinning, with some success but concerns about the long-term benefits of Minimalist. They plan to continue Minoxidil and finasteride for another year before considering a hair transplant.

      community ASCEplus HRLV Exosomes with microneedling

      in Product  1 upvotes 2 years ago
      The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

      community Switching from Finasteride to RU58841?

      in General  168 upvotes 7 months ago
      The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.

      community Clascoterone phase 3 results are out!

      in Treatment  78 upvotes 4 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Been diagnosed with mpb and acute TE

      in Chat  2 upvotes 7 months ago
      A 21-year-old male diagnosed with telogen effluvium and male pattern baldness started taking finasteride, which initially slowed hair shedding and slightly thickened hair. The doctor recommended iron and vitamin D supplements, and the user is considering minoxidil but wants to stabilize shedding first.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  12 upvotes 1 year ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 6 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community HMI-115 when will it be available

      in Research/Science  15 upvotes 3 years ago
      The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 2 years ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Solo use of Pyrilutamide: UPDATE

      in Update  45 upvotes 3 years ago
      A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

      community Still hope on Kintor due to the new announcement

      in Treatment  18 upvotes 2 years ago
      The conversation is about Kintor's announcement indicating continued hope for their product KX-826 as a treatment for Alopecia Androgenetica. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Pyrilutamide/KX-826 for women?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide/KX-826 is being considered as a potential treatment for female androgenetic alopecia (AGA), but its high cost and limited data on effectiveness are concerns. Kintor markets it for both men and women.

      community Winlevi coming out in 2019

       16 upvotes 7 years ago
      The conversation discusses the potential release of Winlevi in 2019 by Cassiopeia for hair loss treatment. It suggests a regimen combining minoxidil, Winlevi, Nizoral, and possibly dermarolling, with a comment mentioning Breezula as an alternative to finasteride without side effects.

      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 2 years ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community ET-02 Now Recruiting in Texas for Phase 1

      in Research/Science  20 upvotes 1 year ago
      Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.