community How to make topical melatonin?
The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.
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990-1000 / 1000+ resultscommunity Diffuse thinning chronicles pt. 2
A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.
community Anyone with high glucose, insulin resistance, pre-diabetes or diabetes notice any regrowth after starting treatment?
A 21-year-old male with advanced hair loss (NW7) started using finasteride and minoxidil 10 months ago but hasn't seen much progress. He is pre-diabetic with stage 1 hypertension and is seeking insights on whether treating these conditions could improve hair regrowth.
community Realistically how much gains am I leaving at the table by taking oral min and not microneedling?
The user is considering adding microneedling to their current hair loss regimen, which includes 1mg finasteride daily, 1.25mg oral minoxidil twice daily, and Nizoral once a week. Opinions on microneedling's effectiveness vary, but some suggest it could enhance results.
community Creatine, my hair loss, and my DHT levels. An anecdote with lab values.
Increased hair loss after starting a 10g daily creatine regimen, possibly linked to elevated DHT levels despite dutasteride use. Stopping creatine reduced shedding, but the exact cause is uncertain, with discussions on exercise and lifestyle impacts.
community Why HMI115 should work if it doesn’t affect dht?
Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).
community Alfatradiol 1% study rebuttal.
Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.
community 126 Days of Fin/Min/Niz/Microneedling
User shared 126-day progress using Fin/Min/Niz/Microneedling for hair loss. Others discussed microneedling depth, results timeline, frontal coverage, and switching to Dutasteride.
community GT20029 China Phase II Trial For AGA Reached Primary Endpoint
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
community GT20029 Phase 2 results are out
GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.