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      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 3 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Update after 14 months posted last September

      in Minoxidil  871 upvotes 6 months ago
      The user successfully regrew hair using 1.2mg finasteride and 3mg minoxidil daily, without a hair transplant. They experienced significant improvement over 14 months, leading to positive changes in their appearance and confidence.

      community KX 826 x Hair Loss - The Last Dance

      in Satire  7 upvotes 3 years ago
      The conversation humorously discusses hair loss treatments, mentioning Minoxidil, finasteride, and RU58841. It suggests that affordable genetic therapy could be the ultimate solution.

      community In God We Trust, Topical Fin/Min with existing ADHD issues

      in Chat  19 upvotes 1 year ago
      A 27-year-old male with ADHD is experiencing hair thinning and is starting a treatment with topical finasteride (0.025%) and minoxidil (5%). He is addressing high prolactin levels and low vitamin D, while managing side effects from ADHD medication.

      community Any experiences with Ptd-dbm??

      in Research/Science  5 upvotes 3 weeks ago
      The user experienced reduced hair loss using an online serum but found it too expensive and is seeking a vendor for ptd-dbm. They are also interested in KY19382 but are unable to find it.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 9 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

      in Technology  31 upvotes 3 years ago
      A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

      community Stopping finasteride for chemo

      in Finasteride/Dutasteride  108 upvotes 1 year ago
      A user diagnosed with lymphoma is advised to stop finasteride during chemotherapy, with suggestions to consider treatments like Dutasteride and Minoxidil post-recovery. The focus is on prioritizing health over hair loss, with encouragement and advice from others who have experienced similar situations.

      community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

      in Treatment  27 upvotes 2 years ago
      The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

      community 21m, curious about what's going on with my hair

       6 upvotes 11 years ago
      A 21-year-old male with a thyroid condition noticed his hair thinning uniformly without a receding hairline. He is considering using a 5ARI to prevent further baldness if he starts TRT.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community A reminder that Telogen Effluvium could look like MPB; my progress

      in Progress Pictures  30 upvotes 3 years ago
      A 19-year-old male experienced significant hair loss, initially thought to be male pattern baldness (MPB), and used minoxidil and briefly finasteride. After realizing the issue was telogen effluvium (TE), he improved his diet and supplemented with vitamins, which led to substantial hair regrowth.

      community Losing ground on finasteride, 14 month update

      in Progress Pictures  11 upvotes 1 year ago
      The conversation is about a user experiencing hair loss despite using finasteride for 14 months, with suggestions to try other treatments like dutasteride or minoxidil. The user is hesitant to use minoxidil due to a family history of heart problems.

      community NW5 at 19. How many grafts do I need?

      in Transplants  138 upvotes 2 years ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community Silicon Valley backed company aims to cure hair loss

      in Technology  53 upvotes 4 years ago
      A Silicon Valley-backed company aims to cure hair loss. Exciting advancements include mRNA therapies, gene editing, hair cloning, AR degraders, anti-androgens, cell-based rejuvenation, and AI-based drug discovery, with hopes for FDA approval of GT20029 within 10 years.

      community Effect of melatonin on aromatase expression

      in Update  5 upvotes 4 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 11 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community This guy is 113 and has more hair than most people on here.

      in Satire  985 upvotes 5 years ago
      A 113 year old man who has more hair than most people, and the conversation is discussing potential genetic factors that may be responsible for this. Possible treatments such as dermarolling and minoxidil, finasteride, and RU58841 are mentioned.

      community Just got some test results back.

      in Finasteride/Dutasteride  5 upvotes 5 years ago
      The user received hormone test results showing normal estradiol and testosterone levels, low SHBG, and normal free androgen index. They are considering starting finasteride but are concerned due to being slightly overweight.