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      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 7 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 7 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community 1 year of .5mg oral dut, .3% topical fin and 6% topical min everyday

      in Finasteride/Dutasteride  88 upvotes 9 months ago
      A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.

      community Started fin + advice needed (19m)

      in Finasteride/Dutasteride  28 upvotes 10 months ago
      A 19-year-old using finasteride for hair loss seeks advice on additional treatments. Suggestions include microneedling, minoxidil, and ketoconazole shampoo, with concerns about side effects discussed.

      community [22m] Is it time for a transplant?

      in Progress Pictures  56 upvotes 11 months ago
      A 22-year-old is experiencing aggressive hair loss despite using minoxidil and finasteride and is considering a hair transplant but lacks funds. The discussion includes advice on treatments like dutasteride, microneedling, and lifestyle changes, with mixed opinions on the timing and effectiveness of a transplant at a young age.
      Eliminate/Confirm AGA based on blood report

      community Eliminate/Confirm AGA based on blood report

      in General  126 upvotes 11 months ago
      A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

      community Almost 4 months of fin/min… quit waiting!!!

      in Is this regrowth?  461 upvotes 11 months ago
      A user shared their positive experience with hair regrowth using finasteride, minoxidil, dermastamping, and keto shampoo, noting significant improvement in four months without major side effects. They encouraged others to start treatment early and shared tips for application and tracking progress.

      community Hairloss has destroyed my Life completely

      in Chat  339 upvotes 11 months ago
      A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

      community PSA: Check your vitamin D levels!

      in Treatment  317 upvotes 11 months ago
      Low vitamin D levels can negatively impact hair growth, and supplementing with vitamin D, along with treatments like finasteride and minoxidil, may help improve hair health. Quitting smoking and ensuring adequate vitamin B12 and K2 intake are also suggested to support hair regrowth.

      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 11 months ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community My Journey on Fin + Min (19M giving up)

      in Finasteride/Dutasteride  20 upvotes 1 year ago
      A 19-year-old tried oral minoxidil and finasteride for hair loss but experienced side effects like fatigue, dry eyes, and lack of motivation, leading to discontinuation. Suggestions included trying topical treatments, dutasteride, or accepting hair loss.

      community 6 months finasteride and 5 months dutasteride

      in Progress Pictures  19 upvotes 1 year ago
      A 22-year-old switched from finasteride to dutasteride for hair loss treatment, also using RU58841, and is managing hypothyroidism. Despite ongoing shedding, they report some improvement and plan to continue dutasteride for a year before considering minoxidil.

      community 24M still losing on Dut and Oral Min

      in Update  26 upvotes 1 year ago
      A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  145 upvotes 1 year ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Finasteride progress 0.25-0.5mg 11 months

      in Progress Pictures  378 upvotes 1 year ago
      User shared progress pictures showing significant hair improvement after using finasteride (0.25-0.5mg daily) for 11 months. Other treatments like microneedling, ketoconazole, and scalp massage were mentioned but not used consistently.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 2 years ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community started RU58841 today and am panicing

      in Treatment  8 upvotes 2 years ago
      A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

      community I lost the fight against MPB at age 22 despite being on treatments.

      in Finasteride/Dutasteride  72 upvotes 2 years ago
      The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.