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630-660 / 1000+ resultscommunity How can I safely apply RU58841 whilst I have children in the house?
RU58841 is not recommended for use around children due to potential exposure risks. Alternatives like CB-03-01 might be considered, but further research is advised.
community Over 13 months on 5% minoxidil and 6 months on finastride
A user stopped using 5% minoxidil and finasteride despite positive results to focus on enjoying life without the stress of hair care. They prioritize personal happiness and acceptance over hair maintenance.
community How has hairloss/balding affected your anxiety or OCD, and how do you cope with it?
community Hormones and hair loss (23F)
The user is experiencing severe hair loss, possibly due to telogen effluvium, after stress, poor nutrition, and hormonal changes. They are using Nizoral and supplements but are considering hormonal treatments like spironolactone despite previous side effects.
community Wasted a whole year on an expensive "natural treatment" just to realize I am a hyper responder.
community Since there is so much hype for cosmeRNA and HMI-115...
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
community Reflex Hyperandrogenicty: How I recovered from it
The user experienced severe hair shedding from RU58841 and recovered by stopping its use and starting treatments including Minoxidil, Rosemary Verbenone, Stemoxydine, Aminexil, copper peptide serum, and specific shampoos. They also consistently used oral Finasteride and plan to try Minoxidil 10%.
community Experience with Strut topicals?
A user has been using a topical hair loss treatment with finasteride, minoxidil, and tretinoin for 4 years without satisfactory results and is considering switching to a different product due to concerns about effectiveness and company reliability. They are seeking others' experiences with Strut and alternative products before making a change.
community Transitioning off daily Oral Dutasteride (0.5mg) for long-term (multi-decade) maintenance. Which protocol is best?
community I'm tired of this never ending fight. When the results will become real and not just a temporary thing?
The user is frustrated with ongoing hair loss despite using treatments like finasteride, dutasteride, minoxidil, RU58841, and others. They express concern over the lack of improvement in hair density and the emotional toll it takes.
community Brutal... RU58841 , is that true ?
The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Concerns are raised about the lack of studies on RU58841 and its potential effects.
community 1.5 year journey on meds since 2025
community FINALLY stopped shedding constantly after 1 year on 5ar inhibitors!! Moral of the story: Just wait
After using finasteride for 7 months and dutasteride for 5 months, the user experienced a significant reduction in hair shedding and scalp itchiness. They advise patience with hair loss treatments and suggest focusing on a good haircut and reducing stress.
community Possible causes for crown/top of head thinning even while on a “nuclear” stack? (MTF + fin + microneedling)
Trans woman experiences hair thinning despite low testosterone and treatments like finasteride and microneedling. Possible causes discussed include past eating disorder and current stack of medications and supplements.
community 24 (F), shedding hair for nearly 8-9 months
A 24-year-old female experiencing hair shedding for 8-9 months suspects it may be due to stress or birth control pills. She plans to consult a dermatologist and gynecologist for further insight.
community Is anyone else experiencing hyper-trichosis' from oral Castor Oil?
The conversation is about experiencing hyper-trichosis from taking oral Castor Oil. The user reports increased hair growth on the stomach and legs but is not concerned as it is harmless and will stop when the treatment stops.
community Federal Grant Cuts have impacted PP405 related research
Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.
community Progress or lack of (on Fin since 3 years)
BigLu2012 tried various hair loss treatments for 3 years, including Fin, Min, and RU, but experienced side effects and worsening hair condition. Ready-Character1581 suggested focusing on mental health and not stressing about hair, as it looks better than most.
community Taking Potassium Chloride and Magnesium made minoxidil-induced palpitations 0
Taking potassium chloride and magnesium stopped minoxidil-induced palpitations. The user is considering continuing minoxidil with these supplements.
community Is there anyone longterm on ru58841? Does it actually stop working?
RU58841 is discussed as a hair loss treatment, with concerns about its effectiveness diminishing after two years due to androgen receptor upregulation. The user is hesitant to start using it, fearing it may worsen their condition over time.
community Trying to regrow crown been on Fin for 4.5 years
The user has been on finasteride for 4.5 years and minoxidil for 10 years, maintaining hair but not regrowing much on the crown and temples. They are considering using a dermastamp more frequently and possibly trying RU58841, but are hesitant about dutasteride due to concerns about side effects and DHT suppression.
community Tretinoin buffering before minoxidil
community Mental health check for anyone feeling down in this subreddit.
Hair loss is distressing, with treatments like finasteride, minoxidil, and spironolactone commonly used despite potential side effects. Emphasis is placed on maintaining mental health and self-worth beyond hair appearance.
community Scalp tension, massage therapy, and Botox! Let’s talk about it!
community Deep wrinkles in last year since starting oral minoxidil? Anyone else?
A user noticed deeper facial wrinkles since starting oral minoxidil in February 2023 and is concerned about its effects on collagen production. Other factors include past accutane use, high stress, poor sleep, and COVID-19.
community I have Post PP405 Syndrome(PPS). Should I start a foundation?
The conversation humorously discusses the fictional "Post PP405 Syndrome" and the idea of starting a foundation or cult around it. It mentions skepticism about the effectiveness of PP405 and jokes about future therapies.
community Suffering from success. So much hair now that i need to tie it up to keep it out my eyes. 16ish months.
The user experienced significant hair regrowth using minoxidil, microneedling, and estrogen, leading to a need to tie their hair back. They attribute the success to estrogen suppressing testosterone, alongside their routine of minoxidil, microneedling, and supplements.
community Balding without a family history
The user is experiencing hair loss without a family history and suspects stress or telogen effluvium (TE) as the cause, despite using finasteride without results. Others suggest stress, vitamin deficiencies, or other conditions could be factors, and some mention that balding can occur without a family history.
community Fin & Min re-bound effects (over 20+ years)
The user experienced hair thinning and used Minoxidil and Finasteride over 20+ years, with periods of stopping and restarting treatment, and eventually had a hair transplant. They are considering restarting Minoxidil and Finasteride and are curious about the effectiveness and potential shedding after resuming the treatment.