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720-750 / 1000+ resultscommunity (4m - 6m fin) Still feel like it getting worse
community How the hell am I still losing hair
The user has been experiencing sudden and aggressive hair shedding despite using oral dutasteride and topical minoxidil for six years, and recently added topical finasteride without improvement. Possible causes discussed include stress-related hair loss, dietary changes, or high DHT sensitivity, with suggestions to consult a doctor and consider adjusting treatments.
community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?
community Any men here taking oral spironolactone?
community concerns about starting minoxidil
An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.
community HT scheduled. Am I over reacting?
The user has scheduled a hair transplant after stabilizing hair loss with finasteride and minoxidil, considering additional dermarolling. They are advised to use 2500-3000 grafts conservatively for temple filling without lowering the hairline too much.
community Can this fate be avoided? Or must i simply accept it.
A 19-year-old is experiencing early hair loss, possibly due to oily skin, stress, poor diet, and lack of sleep. They have tried ketoconazole shampoo without success and plan to visit a dermatologist for further advice.
community Is RU daily dosing from 100mg to 17.5mg safe long term?
The user is considering reducing RU58841 dosage from 100mg to 17.5mg for long-term safety due to brain fog issues from finasteride. They apply RU58841 only to the front of the scalp where thinning occurs.
community Any adderall / vyvanse users here?
Adderall and Vyvanse may contribute to hair loss by stressing the dopamine system and increasing cortisol levels. Users discuss potential treatments like Minoxidil, finasteride, and RU58841 for managing hair loss.
community 22 Months Treatment update - fin/dut/min
community i think i have finally found my retrogade alopecia triggers
The user experienced severe scalp itching and hair loss while on dutasteride, which they linked to caffeine and masturbation. They plan to cut out both to see if their hair density improves.
community anyone randomly have a insane shed while on fin long term? is this a sign that fin alone isnt enough?
The user experienced significant hair shedding despite long-term use of finasteride and minoxidil, considering switching to dutasteride and increasing minoxidil dosage. Suggestions included trying topical minoxidil and adding a topical antiandrogen, but avoiding RU58841.
community 5 months of consistent thorough routine, crown hasn’t changed.
The user has been using a combination of oral and topical minoxidil, topical finasteride, RU58841, Nizoral, and microneedling for hair loss treatment. They report improvement in hair thickness except for the crown area, which has not changed.
community Oral min 12 months dut 8 months still shedding a lot and itching 20yo severe diffuse thinning. Sub won’t let me upload pics so please read..
A 20-year-old is experiencing severe diffuse thinning and shedding despite using oral minoxidil for 12 months and dutasteride for 8 months, after previously trying finasteride. They are frustrated with the lack of improvement and considering trying RU58841.
community Reversing Hairloss with 7α-Methyl-19-Nortestosteron aka Trestolone
The user experienced significant hair regrowth using Trestolone, GHK-Cu, and Minoxidil. They avoided Finasteride due to concerns about side effects and noted that their approach reduced androgenic load, contributing to hair regrowth.
community After praising finasteride on this sub for a while I realised it gave me Brain Fog. I think its related to inhibiting GABA and interferring with mirtazapine (an antidepressant).
community I can’t continue using oral minoxidil. I want to so badly though!
The user experienced anxiety and heart pounding from oral minoxidil, despite its effectiveness, and switched back to topical minoxidil. After managing anxiety, they found oral minoxidil more effective, but side effects differ for each person.
community Insane MTF recovery 18 months blocking androgens
Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.
community Insane shed 3 months on Fin + Min Oral
community post transplant / post finasteride
community Should i be worried dut 6 months
The user has been using finasteride and minoxidil, then switched to dutasteride and minoxidil for six months without significant results, noticing thinning after increasing creatine dosage. They plan to consult a dermatologist to explore potential causes beyond androgenetic alopecia.
community 5MG MIN Crazy hypertrichosis on eyebrows and forehead emerging? How to manage?
Minoxidil use led to excessive eyebrow and forehead hair growth, prompting grooming advice like waxing, tweezing, and shaving. Some suggested reducing dosage or considering electrolysis for permanent hair removal.
community Has the user in the HMI-115 trial shared his photos now since it's April?
A user who was part of an ongoing trial for a prolactin blocker and had regrowth, but the progress photos were not shared due to negative reactions from other users. Treatments mentioned include HMI-115, Minoxidil, Finasteride, and RU58841.
community Lowering scalp prolactine - Any ideas ?
The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.
community Rejux-3x - the copper peptide combo that tressless overlooks.
Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.
community How long after starting RU58841 does pre-existing shedding stop?
The user started shedding hair after beginning testosterone replacement therapy (TRT) despite using dutasteride and minoxidil, and added RU58841 to address the shedding. They reduced their TRT dose and hope RU58841 will stop the shedding quickly.
community Hyper responder turned rapid diffuser despite maximal therapy — looking for specialist recommendations
Despite using treatments like Dutasteride, Minoxidil, RU58841, and GHK-Cu injections, the individual continues to experience aggressive hair thinning and is seeking a specialist for further help. Suggestions include trying finasteride, dermarolling, or another hair transplant.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Double jaw surgery induced intense shed, pyrilutamide stopped it in its tracks
After jaw surgery caused intense hair shedding and scalp itch, using pyrilutamide significantly reduced these symptoms. It's suggested to test pyrilutamide for authenticity before use, despite positive personal experience with the product from MV Supplements.