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      community Figuring out my own experimental protocol

      in Treatment  11 upvotes 3 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community Compounded minox + tretinoin topical

      in Product  2 upvotes 2 years ago
      A user is seeking recommendations for a minoxidil and tretinoin topical solution, including dosage and purchase locations in the US. They are looking for effective hair loss treatments.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community The mystery of Azelaic Acid

       4 upvotes 11 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community Minxodil collegen synthesis decrease?

      in Minoxidil  3 upvotes 2 years ago
      Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.

      community Has anyone had luck with low-level laser therapy (LLLT) devices?

      in Question  5 upvotes 8 years ago
      Low-level laser therapy (LLLT) devices may help thicken existing hair but are not effective for regrowing hair on bald areas. Users suggest sticking with finasteride, minoxidil, and dermapenning, as LLLT devices like Capillus are expensive and results are mixed.

      community 0-5 months: almost perfect hair regrowth. But now, after ten months….

      in Update  16 upvotes 1 year ago
      The user experienced significant hair regrowth with topical finasteride, minoxidil, ketoconazole, and dermarolling, but later faced severe hair shedding after stopping dermarolling and reducing ketoconazole use. Suggestions included switching to oral treatments, resuming dermarolling, and considering lifestyle changes.

      community Crown progress Nov 2024 to March 2025. Full recovery possible?

      in Progress Pictures  279 upvotes 1 year ago
      A 29-year-old is using liposomal topical finasteride/minoxidil and low-level light therapy (LLLT) to improve hair growth, showing significant progress in crown recovery. The user prefers liposomal topicals to avoid side effects from oral finasteride and uses the iRestore Essential device for LLLT.

      community 5 months topical minoxidil results

      in Progress Pictures  1247 upvotes 11 months ago
      The conversation is about a user sharing their 5-month progress using topical minoxidil 5% twice daily, ketoconazole shampoo, and vitamin D supplements for hair loss, with plans to add finasteride. The user experienced initial shedding but noticed hair thickening by the fourth month, and is seeking advice for dryness caused by minoxidil.

      community Anyone have multi week sheds from ru?

      in Chat  2 upvotes 1 year ago
      The user experienced increased hair shedding after using RU58841, despite initial improvements in scalp condition and appearance. They are considering stopping RU58841 to see if shedding decreases.

      community Am i too obsessed with hair loss prevention? And Is This obsession healty? Am i the only one? Look at my collection In This picture: Oral finasteride/ topical finasteride/ minoxidil 5% + tretinoin/ minoxidil 5%/ Alfatradiol 0.025%/Stemoxydine 5%/ dermapen/ketoconazole 1%/viviscal/procyanidin B2.

      in Chat  49 upvotes 4 years ago
      User obsessed with hair loss prevention shares collection of treatments, including oral and topical finasteride, minoxidil, dermapen, and more. Others suggest adding RU58841, laser helmet, and PRP, while some advise dropping certain treatments for long-term manageability.

      community Diffuse thinning chronicles pt. 2

      in Progress Pictures  16 upvotes 2 years ago
      A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  100 upvotes 1 year ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 2 years ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Pyrilutamide: hairloss continues

      in Treatment  12 upvotes 3 years ago
      The conversation is about someone experiencing continued hair loss despite using Pyrilutamide and considering the need for more time or better quality control for the treatment. Another person suggests waiting for the drug to be officially approved due to potential quality issues with current products.

      community 3 month progress pictures RU fin and OM

      in Progress Pictures  42 upvotes 3 years ago
      The user shared progress pictures after three months of using RU58841, finasteride, and OM (oxidative stress modulators) for hair loss treatment. They haven't noticed much change but are seeking feedback on their results.

      community When should I apply topical tretinoin solution?

      in Treatment  4 upvotes 5 years ago
      The conversation discusses applying a topical solution containing 0.01% tretinoin, 1.5% azelaic acid, and 5% minoxidil for hair loss. It is recommended to apply tretinoin at night and use sunscreen during the day to prevent skin damage.

      community Dermatitis and Nizoral

      in Ketoconazole 6 years ago
      A 27-year-old male experienced hair loss and dermatitis, which improved with tea tree oil and neem extract. He is considering using a 2% Ketoconazole solution for further treatment.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 1 year ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Dermaneedling+minox+tretinoin+azaleic acid and hair loss

      in Minoxidil  1 upvotes 5 months ago
      The user stopped oral treatments due to side effects and switched to a regimen of topical minoxidil, tretinoin, azelaic acid, and dermaneedling, with recent addition of topical finasteride. They are questioning the long-term effectiveness of non-hormonal methods and considering hair transplantation.