Hairloss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.
The user is experiencing diffuse hairloss due to high testosterone levels and has tried various treatments including finasteride, minoxidil, nanoxidil, keto/caffeine shampoo, dermarolling, and RU-58841 with limited success. They are seeking advice on safely lowering testosterone levels to manage hairloss.
The user is experiencing hairloss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.
Many people become hyper-aware of hairloss in themselves and others, often leading to feelings of jealousy or self-consciousness. Treatments like finasteride, minoxidil, and dutasteride are commonly discussed as solutions to combat hairloss.
The user changed their hairloss treatment in October/November, experienced increased shedding, and now sees no new hair growth, with a worsening condition and a possible bald spot. They also have severe seborrheic dermatitis, which may be affecting their scalp and hairloss.
Hairloss treatments include finasteride, minoxidil, alfatradiol, vitamins, red light therapy, ketoconazole shampoo, meditation, green tea, leg workouts, and silk pillows. Genetics is emphasized as the primary factor in hair health, with some humor about unconventional methods like drug use affecting hairloss.
The conversation discusses changes in scalp texture and appearance in areas of hairloss, with concerns about the suitability of these areas for hair transplants. Users mention issues like fibrosis, inflammation, and thinner skin, advising caution and consultation with clinics before proceeding with transplants.
OP is using 5% minoxidil and a needler to regrow hair after chemotherapy-induced hairloss. Another user mentions using finasteride and topical minoxidil, noting some improvement in hair density.
A user is experiencing hairloss and is using Morr F 5% Minoxidil, Finasteride Lipid Solution, ketoconazole shampoo, and biotin tablets. They seek advice on the correct application method and hair partitioning.
A user, 42 M, NW 5-6, used oral Dutasteride, Minoxidil, RU58841 topical, micro needling, Nizoral shampoo, saw palmetto gummies, vitamin D gummies, and scalp massages for 2 months. They noticed many small light hairs on previously bald areas and are questioning if these will darken or remain vellus hairs.
The conversation is about hairloss and the conclusion is that genetics play a significant role in hairloss, and lifestyle choices or being a well-adjusted person do not prevent male pattern baldness.
The user experienced tiny vellus hairs from 0.5mg finasteride and 2.5mg minoxidil over 9 months. Topical minoxidil, alfatradiol, and RU58841 applied twice daily for 1.5 months significantly improved temple hair regrowth.
The user is experiencing hairloss and has been using RU58841 but is considering pyrilutamide and minoxidil, avoiding finasteride due to side effects. Another user suggests finasteride or dutasteride as essential, possibly in topical form, while dismissing saw palmetto as ineffective.
Hairloss discussion includes potential HMI-115 treatment. Topical mucuna pruriens shows good results, blocking prolactin possibly more important than blocking DHT.
The conversation discusses hair regrowth, with users sharing experiences and advice on using finasteride, minoxidil, and dermarolling to stimulate hair growth. Many users report seeing small hairs, which they consider a positive sign, though opinions vary on whether these hairs will develop into thicker, terminal hairs.
People with hairloss experience emotional struggles and body dysmorphia. Treatments like minoxidil, finasteride, and dutasteride are used, but results vary and can take time.
The user shared their successful hair regrowth using oral finasteride, minoxidil foam, a custom topical solution, ketoconazole shampoo, and microneedling, resulting in significant improvement at the crown. However, they experienced hairline recession after switching to a topical solution with finasteride and minoxidil, raising concerns about its effectiveness.
A woman experiencing hairloss, exacerbated by wearing a hijab, is seeking advice for her upcoming wedding. She has tried various treatments, including minoxidil, finasteride, and stem cell therapy, and is considering using hair fibers and extensions to cover her scalp.
Why the top of the head is affected by hairloss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.
An 18-year-old diagnosed with male pattern baldness is using probiotics, saw palmetto, pumpkin seed oil, soy isoflavones, biotin, fish oil, quercetin, a multivitamin, and ketoconazole shampoo. Replies suggest these methods are ineffective and recommend finasteride, minoxidil, and a derma roller.
The user is experiencing hair thinning despite using finasteride for three years and is considering trying minoxidil. They are seeking advice on a hairstyle, like a French crop, to manage their hairloss.
The conversation discusses hairloss treatments, specifically finasteride, minoxidil, ketoconazole shampoo, and microneedling, with users experiencing initial success followed by increased shedding and regression. Many users suggest patience, as hair cycles can take years, and some attribute changes to seasonal shedding.
A 22-year-old experiencing intense hairloss across the scalp seeks advice, considering factors like nutrition and genetics. Suggestions include checking vitamin, mineral, and thyroid levels.
A 23-year-old is experiencing hair that is thick at the ends but thin at the roots despite using minoxidil and finasteride for 10 months. They are concerned about whether this is normal or a sign of miniaturization and seek advice on reversing or improving the condition.
The conversation highlights the general public's lack of knowledge about hairloss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.
Hairloss discussion includes Minoxidil and regrowth. Regrowing hairs start light and curly, then become dark and thick; losing temporal peaks is normal.
Hairloss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.
SCUBE3 and GT20029 are potential treatments for hairloss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.