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      community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

      in Chat  17 upvotes 4 years ago
      People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

      community Solution vehicle used by compounding pharmacy

      in Research/Science  1 upvotes 2 years ago
      The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 10 months CB and Oral Minoxidil

      in Progress Pictures  113 upvotes 2 years ago
      A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

      community PSA: Minoxidil 6 months supply is $10 off at Costco

      in Minoxidil  138 upvotes 2 years ago
      The post is about a discount on a 6-month supply of Minoxidil at Costco. The conversation includes users discussing their experiences with purchasing and using Minoxidil, with some mentioning regional price differences and preferences for foam or liquid forms.

      community My nuclear skitzo hairloss stack

      in Finasteride/Dutasteride  5 upvotes 3 months ago
      The conversation discusses a hair loss treatment regimen involving high doses of dutasteride, finasteride, and minoxidil, with concerns about safety and potential side effects. Users advise against the excessive use of these medications, suggesting more moderate approaches and consulting a doctor.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community 1 Year Fin/Min/Niz update

      in Finasteride  14 upvotes 6 years ago
      User tried finasteride, minoxidil, and nizoral for hair loss with minor results. Derma rolling improved hair thickening significantly.

      community The Cure isn't 5 years away; it's already here.

      in Research/Science  1005 upvotes 1 year ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

      community This got rid of my minoxidil itch

      in Product  5 upvotes 2 years ago
      A user found relief from minoxidil-induced scalp itch by using a different product, as Nizoral dried out their scalp and worsened the condition. The conversation focuses on managing side effects of hair loss treatments.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 1 year ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community Difference: GT20029 vs CosmeRNA

      in Treatment  9 upvotes 3 years ago
      GT20029 and CosmeRNA are both potential hair loss treatments; GT20029 breaks down the androgen receptor, while CosmeRNA prevents its production. Continuous use is needed, but less frequently than current treatments like Minoxidil and Finasteride.

      community Finasteride, Minoxidil, Ketoconazole 1 year update

       19 upvotes 10 years ago
      The user used finasteride, minoxidil, and ketoconazole for hair loss prevention. After one year, there was no noticeable hair regrowth, but no further hair loss occurred.

      community 3 months in with 1mg fin and topical minox

      in Progress Pictures  201 upvotes 1 month ago
      The user experienced improved hair health and density after three months using 1mg finasteride and topical minoxidil twice daily, with no side effects. They also use ketoconazole 2% twice weekly and purchase their medications from Amazon.

      community For those of you applying Pyrilutamide, what's your plan B?

      in Treatment  6 upvotes 2 years ago
      The user switched from Pyrilutamide to RU58841, changed their Minoxidil solution, and continued using low-dose Finasteride, derma rolling, and specific shampoo. They asked others about their plans after Pyrilutamide's disappointing results.

      community Combining topicals together or use them separately

      in Chat  4 upvotes 9 months ago
      Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.

      community What the hell happened to Breezula?

      in Research/Science  14 upvotes 10 months ago
      Breezula (clascoterone) Phase 3 hair loss trial results are delayed, with no official updates yet. The acne version is approved, but hair loss results are still pending.

      community GHK-Cu peptide injections - what is your experience?

      in Research/Science  13 upvotes 3 months ago
      GHK-Cu peptide injections are discussed for hair growth, but users report mixed results and suggest focusing on DHT management first. Some users combine GHK-Cu with treatments like Minoxidil and Dutasteride, but emphasize its benefits for skin rather than hair.

      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community inactive ingredients of Sandoz Finasteride 5mg compared too Proscar and Propecia?

       3 upvotes 10 years ago
      The conversation discusses the differences in inactive ingredients between Sandoz 5mg Finasteride and Proscar/Propecia, questioning the purpose of certain additives like Docusate sodium. It seeks to determine if these differences affect the effectiveness of the treatment for hair loss.