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      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 1 year ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community You would never even know - Matthew McConaughey

      in Chat  1372 upvotes 5 months ago
      Matthew McConaughey likely maintains his hair using finasteride, minoxidil, hair transplants, and possibly a hair system. Products like Reginix or rosemary oil are not considered as effective as these treatments.

      community Dermatologist recommends Evening-Primrose Oil

      in Treatment  2 upvotes 5 years ago
      A dermatologist recommended Evening-Primrose Oil, Biotin, Zinc, Vitamin D, and K to block DHT and address hair loss. The user is considering these alternatives to prescription drugs like finasteride.

      community Does drinking coffee have any effect on hairloss?

      in Research/Science  4 upvotes 5 years ago
      Coffee's effect on hair loss is debated, with some suggesting it may exacerbate hair loss due to vasoconstriction, while others believe it could have positive effects. Topical caffeine might be beneficial, but ingesting it could potentially inhibit vitamin D receptors.

      community at what point does RCP no longer benefit?

      in Treatment  5 upvotes 1 year ago
      A user is using Minoxidil, finasteride, saw palmetto, and Minimalist RCP serum to address hair thinning, with some success but concerns about the long-term benefits of Minimalist. They plan to continue Minoxidil and finasteride for another year before considering a hair transplant.

      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 2 years ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community It’s all about the stem cells…

      in Research/Science  52 upvotes 4 years ago
      Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

      community Any long term RU55841 / CB-03-01 / Eucapil users here?

      in Research/Science  9 upvotes 5 years ago
      Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.

      community 300 days of fin/min/microneedling/nizoral

      in Progress Pictures  242 upvotes 3 years ago
      Slow, steady progress on hair loss treatments such as finasteride, minoxidil, microneedling and Nizoral; the need for patience when using these treatments over a period of months or years; and how to deal with discouragement due to slow progress.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Anyone tried CB-03-01?does it work ?

      in Research/Science  2 upvotes 9 months ago
      CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

      community Has anyone tried Topical oxytocin?

      in Treatment 2 years ago
      A user reported less hair shedding using melatonin spray and is considering trying topical oxytocin or estrogel for hair growth, but is concerned about potential side effects like breast development. Topical oxytocin has been found to promote hair growth by increasing growth factors.

      community M28, Surprising 20 day progress

      in Progress Pictures  5 upvotes 1 year ago
      A 28-year-old shared surprising hair regrowth progress after 20 days using topical minoxidil, micro needling, GHK-cu, and BPC-157 injections. The user noted a significant reduction in their bald spot and overall hair improvement.

      community Update and new paper from Dr tsuji

      in Update  25 upvotes 7 years ago
      Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

      community Ronaldo and his Brothers Hairline (10 years difference)

      in Chat  498 upvotes 1 year ago
      Ronaldo's hairline remains sharp, while his brother's is receding. Opinions vary on whether Ronaldo uses treatments like finasteride or has had hair transplants, with some attributing his hairline to genetics and others to possible medical interventions.

      community why are beard gains on min usually permanent?

      in Minoxidil  43 upvotes 7 months ago
      Beard gains from minoxidil are usually permanent due to facial hair follicles' lower sensitivity to DHT. Scalp hair requires ongoing DHT suppression with treatments like finasteride, dutasteride, and RU58841 to maintain gains after stopping minoxidil.

      community Cosmo Pharma 2025 Investor Day Report

      in Research/Science  5 upvotes 9 months ago
      Cosmo Pharma plans to release Breezula, a hair loss treatment, with expected FDA approval in 2027, but concerns arise over its high potential cost of $225/month. Users express skepticism about its effectiveness compared to cheaper alternatives like finasteride and minoxidil.

      community How to properly use and store RU58841?

      in Treatment  2 upvotes 2 months ago
      The user is using RU58841, dutasteride, and minoxidil for hair loss, storing RU58841 in the fridge and applying it nightly. They report more baby hairs on the temples but are unsure if it's due to new growth or miniaturization, and seek advice on mixing and results from RU58841.