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3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

A 29-year-old is experiencing diffuse hair loss and has been using minoxidil without success. They are now trying a routine with oral minoxidil, topical finasteride, and dermarolling, but are unsure about the effectiveness and legitimacy of the products.

The conversation discusses a hair loss treatment routine involving daily minoxidil, finasteride, micro-needling, rosemary oil, and biotin supplements. The user shares personal experiences, noting no side effects from finasteride and emphasizing the importance of a healthy lifestyle in preventing hair loss.

The user is observing potential hair regrowth at day 46 using 1mg oral finasteride, 2.5mg oral minoxidil, 5% topical minoxidil, biotin, vitamin D, fish oil, and weekly dermal rolling. They are optimistic about the results despite skepticism from others.

Intermittent finasteride dosing, like taking it every third day, may reduce side effects while still lowering DHT levels. Users report side effects such as brain fog and weaker erections, which often subside after stopping the drug.

The user is experiencing hair shedding despite using finasteride, minoxidil, and microneedling, and is concerned about the non-linear progress. Other users share similar experiences, suggesting shedding is normal and cyclical, with some recommending less frequent microneedling.

A 24-year-old uses microneedling, tretinoin, topical and oral minoxidil, and oral finasteride for hair growth, noticing baby hair growth and initial side effects that resolved. Another user shares a similar regimen, excluding finasteride.

Apply wax and sunscreen at least 30 minutes after minoxidil to ensure effectiveness. Avoid showering or exercising for 4 hours post-application.

The post discusses a user's hair loss treatment routine, which includes daily 1mg finasteride, twice daily topical rogaine, biotin vitamin intake, and a new microneedling regimen of 0.5mm three times a week. The user is turning 24 next month.

The conversation discusses hair regrowth after 100 days using 5mg Minoxidil and 0.5mg Dutasteride, focusing on changes in the temples and hairline. Users debate the effectiveness due to inconsistent photo comparisons.

The conversation discusses the effectiveness of adding topical caffeine serum to a hair loss treatment routine that includes minoxidil and finasteride. Users suggest alternatives like stemoxidine, alphatradiol, and pyrilutamide, noting that evidence for caffeine's effectiveness is weak.

The user maintained their hair using daily 1mg finasteride, topical minoxidil, vitamins, and a derma roller every 15-20 days. Suggestions included switching to dutasteride and oral minoxidil.

User shared 8-month progress using daily topical Fin/Min, weekly microneedling, and supplements (biotin, zinc, saw palmetto, collagen). Others praised hairline regrowth and requested temple photos.

The conversation is about finding the best topical caffeine and melatonin products to use with minoxidil, and possibly adding essential oils. The user seeks recommendations for effective combinations to enhance hair growth.

The conversation is about whether to split 1mg finasteride pills to take 0.5mg daily or take 1mg every other day to save money and reduce side effects. There are concerns about the effectiveness of splitting due to the pill's coating and alternating due to its half-life.

A user accidentally ingested minoxidil instead of melatonin, leading to a humorous discussion about similar mix-ups and the effects of minoxidil. The user now stores the bottles separately to avoid future mistakes.

People are using topical melatonin for diffuse thinning and retrograde alopecia. They are discussing the best brands and application methods.

The person is using 1mg of finasteride daily, 2mg of minoxidil, and weekly dermarolling with a 1mm needle. They sometimes use topical minoxidil as well.

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

Finasteride can affect hormone levels within two weeks, and a break of several weeks is recommended for baseline results. Monitoring E2 and testosterone is suggested to assess the risk of gynecomastia.

The user is using a hair loss treatment regimen that includes double the recommended dose of Minoxidil foam once nightly, a mix of RU58841 and stemoxydine after the Minoxidil dries, ketoconazole every other day, and weekly microneedling with alternating depths. They are also considering starting finasteride soon.

A 24-year-old female experiencing hair shedding for 8-9 months suspects it may be due to stress or birth control pills. She plans to consult a dermatologist and gynecologist for further insight.

The user had a hair transplant in 2020 and later learned they needed to continue medication for hair loss. They shared a 5-month timelapse video of their hair regrowth using topical finasteride/minoxidil, microneedling every 3 weeks, and ketoconazole.

The user has scheduled a hair transplant after stabilizing hair loss with finasteride and minoxidil, considering additional dermarolling. They are advised to use 2500-3000 grafts conservatively for temple filling without lowering the hairline too much.

The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hair growth but advising against mixing it directly into the solution due to potential instability.

A user experienced a "watery belly" and cellulite after starting finasteride, despite maintaining a disciplined fitness routine. Others suggest checking hormone levels, as changes in DHT and estrogen could affect fat metabolism, but age might also be a factor.

Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

The post and conversation are about a user sharing their hair loss treatment routine, which includes dermarolling, Minoxidil, topical finasteride, biotin, Nizoral, castor oil, and a power laser comb. Replies indicate positive feedback and noticeable hair growth.

A user wants to try melatonin for hair loss by mixing melatonin powder with a topical oil serum. They are asking if this mixture is possible and effective.