Amplifica starting clinicaltrials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.
Breezula passed a clinicaltrial in August and there are questions about its availability in 2021 and potential delays due to Covid. No specific treatments were discussed.
A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinicaltrials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.
A user shared their positive experience with a clinicaltrial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.
The conversation is about the release timeline for clinicaltrial results and the availability of Breezula, a hair loss treatment. The user is not comfortable buying it as a research drug from China.
Hair cloning technology is advancing, with clinicaltrials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.
Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinicaltrials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.
The conversation is about someone looking for specific side effects reported in clinicaltrials for GT20029, a hair loss treatment. No results or data were found on the clinicaltrials site.
The conversation discusses new research on hair growth by Dr. Maksim Plikus, with a call for clinicaltrials to begin. No specific treatments are mentioned.
Pyrilutimide and CB-03-01, two treatments for hair loss, have similar clinicaltrial results despite different binding affinities to androgen receptors. Factors other than binding affinity, like the time a drug stays bound to the receptor, may influence their effectiveness.
The conversation is about the anticipated results of Pelage's Phase 2a clinicaltrial for their topical hair loss treatment, PP405. Users speculate on when the results will be available, noting that delays might indicate less successful outcomes.
Hair follicle regenerative therapy is being developed, with clinicaltrials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.
UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinicaltrials. Minoxidil and finasteride remain common treatments until PP405 becomes available.
Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinicaltrials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.
PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinicaltrials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.
AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinicaltrials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.
Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinicaltrials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.
A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinicaltrials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.
PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinicaltrials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.
SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinicaltrials. No specific updates or new information are provided in the conversation.
A stem cell and adenosine triphosphate cocktail showed promising results in hair regrowth for male and female mice, with potential for future clinicaltrials. Users humorously reacted to the success in mice, expressing hope for human application.
Liposomal formulations of finasteride and minoxidil may enhance drug delivery to the skin and hair follicles more effectively than traditional solutions, potentially improving treatment outcomes. However, more human clinicaltrials are needed to confirm these benefits.
Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinicaltrials are needed to confirm its efficacy and safety.
RU58841 is discussed as a potential hair loss treatment, with comparisons to finasteride. There is interest in leaked trial data, but no official clinical validation or approval for RU58841.
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinicaltrials to ensure safety and efficacy.
The conversation is about hair loss treatments, specifically setipiprant, which the user is considering after experiencing side effects from finasteride and dutasteride. Another user mentions that setipiprant was ineffective in clinicaltrials.
KOSHINE826 is a new anti-hair loss and hair growth solution that claims to effectively control oil, reduce hair fall, and promote real hair growth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinicaltrials.
The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinicaltrials.
A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenic alopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinicaltrial.