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GlossaryClomipramine

tricyclic antidepressant used to treat obsessive-compulsive disorder

Clomipramine, also known by the brand name Anafranil, is a tricyclic antidepressant primarily used to treat obsessive-compulsive disorder (OCD). It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and reduce anxiety.

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community Has anyone tried CB-01-03 aka Clascoterone?

in Research/Science 2 upvotes 1 month ago

Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

in Research/Science 2 upvotes 1 year ago

The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

community cb-03-01 research chem (winlevi/clascoterone cream)

in Technology 3 upvotes 2 years ago

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

in Research/Science 4 upvotes 2 years ago

The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

community Clascoterone powder already available?

in Product 4 upvotes 1 week ago

Clascoterone powder is now available, but it's expensive and not widely discussed due to past ineffective results at higher concentrations. Users are skeptical about its effectiveness and are seeking reliable sources.

community Cassiopea Announces FDA Submission of New Drug Application for Clascoterone Cream 1%, the First New Mechanism of Action for Acne in Nearly 40 Years

in Technology 29 upvotes 6 years ago

The conversation is about a new acne treatment cream called Clascoterone Cream 1%, which is the first new mechanism of action for acne in nearly 40 years. One person joked about hoping their face will be as clean as their bald head after using the cream.

community Taking part in a Clascoterone Study

in Treatment 6 upvotes 2 years ago

The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

community Clascoterone - Why are there so few posts if it’s already on the market?

in Chat 34 upvotes 2 months ago

Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

community Clascoterone - what we have right now

in Research/Science 19 upvotes 1 month ago

Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

community Clascoterone 5% solution infographic

in Update 130 upvotes 4 months ago

Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

community Clascoterone (Winlevi) Update for Canada

in Treatment 15 upvotes 3 years ago

Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)

in Progress Pictures 13 upvotes 2 weeks ago

The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.

community Clascoterone ph3 results ready

in Research/Science 10 upvotes 4 months ago

Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.

community EMA is re-examining Winlevi (clascoterone at lower concentration)

in Treatment 9 upvotes 9 months ago

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

community Clascoterone phase 3 results are out!

in Treatment 81 upvotes 4 months ago

Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

community Persistent Genital Itching on Finasteride Despite Clotrimazole Treatment

in General 31 upvotes 7 months ago

The user experienced genital itching while using finasteride and noticed a yellow bump, which improved with clotrimazole, but the itching persists. The discussion focuses on side effects of finasteride.

community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 2 years ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

community Joining clinical study for Clascoterone (Breezula)

in Research/Science 7 upvotes 1 year ago

The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

community The urge to buy Clascoterone 5% solution

in Research/Science 11 upvotes 4 months ago

Clascoterone 5% solution is not yet commercially available, with only the 1% solution currently sold for acne. Users discuss the potential of Clascoterone as a hair loss treatment, comparing it to other anti-androgens like RU58841 and Eucapil.

community CASSIOPEA ANNOUNCES VERY POSITIVE PHASE II TWELVE MONTHS RESULTS FOR BREEZULA® (CLASCOTERONE) IN TREATING ANDROGENETIC ALOPECIA

in Update 160 upvotes 6 years ago

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

community making a clascoterone lotion from powder

in Technology 2 upvotes 1 year ago

A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 2 weeks ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Clascoterone - clearnet vendor

in Chat 2 upvotes 3 months ago

The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

community Winlevi (clascoterone 1%) anyone trying it

in Treatment 2 upvotes 3 months ago

Winlevi (clascoterone 1%) is being discussed as a potential hair loss treatment. Users are considering its use despite concerns about its delivery method.

community Clascoterone vs RU58841? What’s more effective?

in Treatment 1 upvotes 3 weeks ago

Clascoterone and RU58841 are compared for effectiveness in treating hair loss. The discussion involves treatments like Minoxidil, finasteride, and RU58841.

community Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?

in Research/Science 1 upvotes 2 months ago

The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

community Hair Loss Associated with Escitalopram (anti-depressant). Do SSRIs Affect the Hair Follicle?

in Research/Science 8 upvotes 1 year ago

A 22-year-old male experienced hair loss potentially linked to escitalopram, which stopped after switching to vortioxetine. His depressive symptoms improved with continued treatment.

community CB-03-01 / Breezula Personal Results

in Treatment 16 upvotes 2 months ago

The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

in Treatment 11 upvotes 4 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

community Clascoterone (Winlevi) now approved in Canada

in Product 14 upvotes 2 years ago

The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.