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      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 4 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community Procyanidin B2 Supplement

      in Research/Science  13 upvotes 5 years ago
      User seeks Procyanidin B2 supplement source and asks for dosage comparison. Another user requests study details and apple type importance.

      community Topical caffeine is a common ingredient in formulas to prevent hair loss and to induce hair regrowth. (What’s your take on this?)

      in Treatment  12 upvotes 3 years ago
      The conversation discusses whether topical caffeine is effective for hair loss, with some users questioning its role due to its vasoconstrictive and vasodilative properties, while another suggests that temporary vasoconstriction might be beneficial by promoting angiogenesis. Specific treatments mentioned include caffeine shampoo, which one user believes is ineffective.

      community Crown progress Nov 2024 to March 2025. Full recovery possible?

      in Progress Pictures  279 upvotes 1 year ago
      A 29-year-old is using liposomal topical finasteride/minoxidil and low-level light therapy (LLLT) to improve hair growth, showing significant progress in crown recovery. The user prefers liposomal topicals to avoid side effects from oral finasteride and uses the iRestore Essential device for LLLT.

      community Exosome PRP combined with Dutasteride and Oral Minoxidil?

      in Treatment  1 upvotes 2 months ago
      The user has been using Dutasteride and oral Minoxidil for hair loss but hasn't seen desired results and is considering Advanced PRP with autologous exosomes. Some users suggest these treatments are scams, while others discuss increasing Dutasteride dosage or exploring other options like low-level laser therapy.

      community finasteride microneedling and exosomes

      in Finasteride/Dutasteride  4 upvotes 2 years ago
      The conversation is about a 21-year-old using finasteride, dermarolling, ketoconazole shampoo, hair growth serums, and exosome therapy to treat early-stage thinning on the crown. They are questioning if these treatments are sufficient to improve hair thickness.

      community Lowering dose of Oral Minoxidil?

      in Minoxidil  108 upvotes 1 year ago
      The user plans to lower their oral minoxidil dose from 5 mg to 2.5 mg to reduce side effects like puffiness and hypertrichosis, while also using finasteride and accutane. They are considering caffeine serums for puffiness and discussing dietary changes or switching to topical minoxidil to address bloating.

      community 3 month progress NW5 -- lost cause?

      in Progress Pictures  22 upvotes 3 years ago
      A user is treating their advanced hair loss with a regimen including topical finasteride, minoxidil, hydrocortisone, stem cell serum, peptide serum, multivitamins, he shou wu tea, derma pen, argan oil, and a derma roller. Replies suggest it's too early to judge progress and recommend staying consistent, with one suggesting oral minoxidil as an additional option.

      community Been going strong with treatment for 3 months

      in Progress Pictures  27 upvotes 10 months ago
      The user reports noticeable hair regrowth after using 2.5mg oral minoxidil daily and 2% ketoconazole shampoo every other day for three months. The dermatologist advised against finasteride due to the user's age but mentioned it might be needed later.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Officially Starting Hair Regimen

      in Chat  6 upvotes 3 years ago
      The user is starting a hair loss treatment including topical finasteride/minoxidil, derma rolling, ketoconazole shampoo, vitamins, exercise, and quitting caffeine. They are seeking advice on derma roller needle size, potential side effects, and additional recommendations.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 9 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community I have been applying undiluted, pure 100% peppermint oil to my scalp, 2.5ml a day as an experiment

      in Treatment  90 upvotes 2 years ago
      A user is experimenting with applying undiluted peppermint oil to their scalp daily to stimulate hair growth, based on a rat study where peppermint oil outperformed minoxidil. The user reports immediate hair thickening and increased scalp blood flow, while others in the conversation express skepticism, humor, and concern about the undiluted application.

      community Bleeding too much for other reasons

      in Microneedling  6 upvotes 3 years ago
      The user experienced excessive bleeding during microneedling after consuming caffeine and THC, and is unsure if they should continue with the same routine. They are seeking advice on whether the bleeding is a cause for concern.

      community Bryan Johnson and his Hair routine, what's the point?

      in Hair Systems  24 upvotes 2 months ago
      Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

      community Reducing Scalp Inflammation

      in Treatment  5 upvotes 5 years ago
      The conversation discusses treatments for scalp inflammation, suggesting options like scalp massage, changing shampoos, using aloe vera, Tgel, nizoral shampoo, topical cetirizine, and consulting a dermatologist. Finasteride was mentioned as helpful for reducing inflammation, but with side effects.

      community Korea launches 1st OTC hair loss drug

      in Treatment  29 upvotes 5 years ago
      Korea launched its first OTC oral hair loss drug, dexpanthenol B5. Users discuss its anti-oxidative and anti-inflammatory effects but note a lack of efficacy studies.

      community TH07 by Triple Hair entering phase III trial

      in Research/Science 2 months ago
      A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

      community I use the big 4 to combat but I need to do more

      in Minoxidil  3 upvotes 8 months ago
      The conversation discusses various hair loss treatments, including Minoxidil, Finasteride, Dutasteride, Ketoconazole shampoo, microneedling, and supplements like collagen, biotin, and vitamins. Users suggest additional treatments like red light therapy, scalp massages, and possibly adding RU58841 or Tretinoin.

      community The Theory of BURN THE SCALP. !! PHOTOS ¡¡

      in Update  13 upvotes 1 year ago
      The conversation discusses a user's experiment of "burning the scalp" to treat hair loss, with mixed opinions on its effectiveness. Some suggest returning to proven treatments like finasteride and minoxidil, while others note slight improvements in hair density.

      community What has the evidence been on side effects with CB?

      in Research/Science  4 upvotes 5 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.