Finasteride and dutasteride can prevent hairloss if used early, but they may cause side effects. Many men shave their heads because they are unaware of these treatments or avoid them due to side effects or cost.
Finasteride is a controversial hairloss treatment, with some users experiencing positive results and others facing side effects like erectile dysfunction. The discussion emphasizes the importance of personal choice and informed decision-making.
A user reported significant hair regrowth using only 1mg finasteride daily over 3.5 years, with no side effects. They stressed patience and consistency, seeing noticeable results after two years.
Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.
The conversation discusses identifying permanent hairloss and includes treatments like microneedling and biotin vitamins. The user is unsure whether the reduction in wispy hairs is due to hair revitalization or loss.
A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hairloss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.
The user experienced increased hairloss and scalp itchiness despite using finasteride and plans to resume minoxidil and start microneedling. They are considering using clay, Aveda thickening tonic, and a beanie to manage the appearance of thinning hair.
Corticosterone inhibits GAS6, affecting hair follicle stem-cell activity, with potential implications for stress-related hairloss. Ashwagandha and Vitamin K are suggested for reducing cortisol, but their effectiveness is debated.
Haircell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.
A 20-year-old male has been experiencing hairloss for three years due to a vitamin D deficiency and has seen no improvement after 3.5 months of taking supplements. Another person suggested that if the hairloss follows a pattern, it might be regular baldness rather than due to the deficiency.
The conversation discusses how Caucasian men are more likely to experience hairloss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hairloss, especially in colder climates where it would seem beneficial to retain hair for warmth.
User experienced hairloss from Norwood 3.5 to Norwood 5 with diffuse thinning after using a hair system for 2 years. Tried Redensyl, Capixyl, Bicapil, Biotin, multivitamins, Fin, and Min without significant improvement, seeking advice for hair recovery.
PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hairloss. They are advancing to more detailed trials this year.
Hairloss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.
The post discusses how using finasteride and minoxidil for hairloss resulted in the user's hair changing from straight to wavy. The responses suggest this change indicates healthier, thicker hair and share similar experiences, while also expressing concerns about potential side effects of the treatments.
The conversation is about coping with hairloss and includes advice on improving overall appearance and confidence. Specific hairloss treatments mentioned are not discussed.
The user noticed small circular hairless spots after a buzz cut and has been using finasteride, dutasteride, and oral minoxidil for hairloss. They are experiencing continuous shedding and thinning, and it is suggested they consult a dermatologist for a scalp examination and possible biopsy to determine if it's alopecia areata or androgenetic alopecia.
A woman experienced significant hairloss due to medication, hair coloring, and heat damage, leading her to shave her head and feel distressed. She is considering using wigs and possibly oral minoxidil to manage the situation while her hair regrows.
High frequency ultrasonography and HR-MRI can help identify hair shedding causes like inflammation and fibrosis. The conversation discusses the potential of using these technologies to evaluate treatments like Verteporfin for hair regeneration.
Finasteride is effective for DHT/AR-driven hairloss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hairloss to tailor treatment effectively.
PP405 is a potential hairloss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.
A 22-year-old male experiencing hairloss suspects androgenetic alopecia (AGA) and possibly telogen effluvium (TE), with a noted improvement in scalp itch after adopting a gluten-free diet. He is advised to consider treatments like finasteride or minoxidil and to check iron and ferritin levels.
MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.
The user is experiencing hairloss and has tried natural remedies like hibiscus shampoo and an oil mixture with coconut oil, curry leaves, fenugreek seeds, and castor oil, but saw no lasting improvement. They are advised to consult a dermatologist and consider treatments like finasteride, minoxidil, and Nizoral shampoo.
A 20-year-old female with PCOS is experiencing hairloss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.
Hairloss due to vitamin B12 deficiency is discussed, with some users suggesting supplements and dietary changes, while others recommend medications like finasteride or dutasteride. The conversation highlights differing opinions on the cause of hairloss, with some attributing it to genetics or male pattern baldness.
Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hairloss.
The user experienced hairloss and used minoxidil, biotin shampoo, and supplements like biotin, zinc, fish oil, saw palmetto, and B vitamins, which initially stopped hairloss but did not promote regrowth. They suspect heat causes a dry, flaky scalp leading to hairloss and are considering using a supplementary shampoo and possibly finasteride.
