The conversation is about recommendations for microneedling tools for hair loss, with users suggesting a dermastamp from Koi Beauty and the Derminator 2 with 12-needle cartridges.
Piroctone olamine is more effective than ketoconazole for increasing hair growth and reducing itching and dandruff. Treatments discussed include Minoxidil, finasteride, and RU58841.
Pumpkin seed oil showed a 40% increase in hair count, but its effectiveness is questioned due to other ingredients in the supplement. Users discuss its potential compared to finasteride, with some expressing skepticism and others showing interest.
PP405 is a new hair loss treatment that may outperform minoxidil and finasteride by growing thick hair in bald areas within four weeks. Its release is expected around 2028, but concerns about its long-term efficacy and cost remain.
The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.
Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.
The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.
A user discussed the "Rootique Duo," a device that turns minoxidil into mist for scalp application, but others suggested cheaper alternatives like an AliExpress applicator. Some users prefer traditional methods like droppers or spray nozzles, especially for longer hair.
Microneedling with finasteride, minoxidil, DMSO, and black seed oil shows mixed hair regrowth results. There are concerns about DMSO's safety and effectiveness.
The conversation discusses the effectiveness of combining Laminaria japonica and Cistanche tubulosa extracts for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.
A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.
A user shared an 8-month hair loss treatment progress using daily saw palmetto and biotin capsules, weekly dermarolling, and a scalp lotion mix of castor, jojoba, and rosemary oils, avoiding finasteride and minoxidil due to side effects and cost. The user reported encouraging progress with slight hairline improvement and better crown area, attributing most success to dermarolling.
The user is exploring alternatives to finasteride and dutasteride due to concerns about side effects, and is using rosemary and jojoba oil, ketoconazole, minoxidil, microneedling, multi-peptide serum, saw palmetto, and stinging nettle for hair loss. They are also considering CB 03 01 and spironolactone.
A product called "PP405 Hair Follicle Serum" is being sold on Shopee, claiming to cure baldness without clinical trials or FDA approval, but users are skeptical and refer to it as "snake oil." Some users discuss testing the product's contents, while others share their experiences with hair loss treatments like finasteride.
The conversation is about the effectiveness of Dermarolling for hair loss without using Minoxidil. Some people consider using peppermint oil as an alternative.
The conversation is about using Peppermint or Spearmint oil for hair loss and asks for successful regimens, including brands, carrier oils, and application details. No specific treatments were shared.
The user has been using finasteride, minoxidil, and a derma stamp for 3 months with significant improvement. They are now adding ketoconazole to their routine.
The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.
The conversation humorously discusses using a dermaroller for hair growth, with a playful suggestion of using it on the wrist. It includes references to Minoxidil, finasteride, and RU58841 as treatments.
RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.
The user is considering liposomal minoxidil due to non-response and side effects from other treatments. They are exploring tretinoin with topical minoxidil as an alternative.
The conversation is about finding a legitimate source for Procyanidin B2 or Apple Extract with a clear percentage of Procyanidin B2 for making a topical solution. The user reports thicker and darker body hair after taking Oral Apple Polyphenols extract.
A user shared their 2-month results using Minoxidil 5%, dermarolling, ketoconazole shampoo, and castor oil for hair loss. They stopped using finasteride due to side effects.
Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about their effectiveness compared to existing treatments like minoxidil and finasteride. Some users mention natural oils like olive and macadamia oil, but overall, there's a consensus that these are unlikely to be game changers.
The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.
A user reported that applying castor oil to their eyebrows for two weeks resulted in thicker hair and is considering using it on their scalp to thicken existing hair, not to stop balding. They do not expect it to cure male pattern baldness.
The post discusses using Mucuna pruriens, essential oils, and dermarolling for hair loss treatment. The user also mentions pausing testosterone-boosting herbs due to side effects like acne and hair loss.
The conversation is about finding a source to purchase TrichoSol online for making DIY topical hair loss treatments without ethanol or propylene glycol. The user is seeking advice on where to buy raw TrichoSol.