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960-990 / 1000+ resultscommunity Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
community 5ARI (dutasteride) Associated with Adverse Metabolic Effects
Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.
community AGA evaluation and first steps - BEGINNER MEGAPOST
The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.
community Seriously, why is this man such an angel 😭
Dr. Gary Linkov, a YouTuber and doctor, is praised for his free hair loss advice despite his own struggles with hair loss. Some users discuss the high cost of his consultations and treatments like oral minoxidil and Jak inhibitors.
community Anyone else experiencing scalp inflammation? Get in here!
A user found that taking Zyrtec (Cetirizine) and Advil helped reduce their scalp inflammation and pain, potentially creating a better environment for hair growth. They have not used any other medication for hair loss or scalp issues.
community Am I missing something with pp405?
PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.
community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia
Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.
community Has anyone tried this Ru58841 from Amazon ?
RU58841 from Amazon is unreliable, with users reporting no benefits and side effects like eye swelling and chest pain. Rudirect is recommended for purchasing in Europe.
community Mixing Finasteride with Ordinary Retinol
Mixing finasteride with retinol for a topical solution to avoid irritation from minoxidil. Finasteride and ketoconazole shampoo help with itchiness.
community Can we trust l’oreal clinical study on Stemoxydine 5%? They conducted/founded the research on the Same molecule that they sell, research could be biased!? L’Oreal reported clinical study that showed an increase of 4% in hair density on the patients treated with stemoxydine for 3 months
Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. L'Oreal's study on Stemoxydine 5% claims a 4% increase in hair density after 3 months, but some users question potential bias.
community As a US resident If kx-826 is approved in China would I be able to purchase it or would I have to wait until its approved in the US?
A user inquired about purchasing KX-826 for hair loss if approved in China. Another user provided links to purchase it without waiting for U.S. approval.
community Homemade finasteride foam similar to minoxidil foam
A user is seeking advice on creating a homemade finasteride foam similar to over-the-counter Minoxidil foam, due to issues with glycerin and propylene glycol in their current solutions. They are considering using a mixture of ethanol/alcohol and water for the foam.
community Does This Invalidate PP405 Completely?
PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.
community I don’t think there’s a better feeling than going to those self checkout things and seeing the camera//cctv and seeing a scalp full of hair
The conversation is about hair loss and the effectiveness of treatments like finasteride, with one user expressing satisfaction after seeing hair regrowth on CCTV. Other users share their experiences with hair visibility and discuss the effectiveness of finasteride compared to dutasteride.
community To everyone who cant use FIN and doesnt want to use RU
A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.
community Does anyone put face copper peptides on their scalp?
OP asks if face copper peptides from Sephora can be used on the scalp for hair benefits. User233 suggests AHK-CU is mainly for hair, but GHK-CU can also be used.
community Eucapill and less shedding
Eucapill 2% used for 1 month reduced shedding from 200 to 10/20 hairs daily with no side effects. Finasteride caused side effects like ED and watery semen.
community Scientists discover hair growth signaling molecule SCUBE3 as potential baldness cure- 🧐
Scientists discover SCUBE3 molecule for potential baldness cure. Mice used in research for hair growth signaling.
community Ketoconazole mesotherapy plausible?
The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.
community NW4 -> NW 2.5 (1yr progress) RU 8.5-9% ED and topical Dut .1% + RU 5% 1.5x a week. (+ caffeine redensyl scalp treatment ED)
The conversation discusses hair regrowth progress from Norwood scale 4 to 2.5 over a year using daily 8.5-9% RU58841, topical Dutasteride 0.1%, RU58841 5% 1.5 times a week, and daily caffeine redensyl scalp treatment.
community Topical Solution Mix: Stemoxydine, RU-58841, Alfatradiol, and Tretinoin - Feasibility and Potential Interactions?
A user is considering mixing Stemoxydine, RU-58841, Alfatradiol, and Tretinoin into a single topical solution for hair loss. They are concerned about potential interactions that could reduce the effectiveness of these ingredients.
community Is PP405 formula available in grey market?
The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.
community Is EAA good or bad for hair? I cant find Any information about it.
The conversation is about whether an EAA supplement affects hair health. The user lists the ingredients but does not receive a definitive answer.
community Scalp Calcification - Inflamation
A young male in his twenties discusses hair loss, mentioning the use of Minoxidil, topical finasteride, and occasional derma rolling. He inquires about scalp inflammation, fibrosis, and the potential benefits of magnesium oil and scalp massages for improving blood flow and hair health.
community Topical latanoprost chance of eye color change?
The user is using oral minoxidil for hair growth and is considering adding topical latanoprost, but is concerned about potential eye color change. They are seeking advice on the effectiveness of latanoprost for hair thickening and the risk of eye color change.
community Just ordered RU powder, a scale, beaker, ethanol and PG. This will be my final attempt.
The user is trying RU58841, oral minoxidil, and dermarolling to combat hair loss caused by increased scalp testosterone after using finasteride and dutasteride. They plan to document their results.
community Spironolactone or bicalutamide prescription
The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.
community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle
This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.
community Caffeine in hair care – does it really help?
Caffeine in hair care can support hair growth but is not a standalone solution; it's best used in combination with other treatments like minoxidil and finasteride. Some products combine caffeine with these treatments for enhanced effects.