Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.
TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
The conversation is about hair regrowth treatments using minoxidil, finasteride, tretinoin, and ketoconazole shampoo. Users discuss their experiences, including side effects, shedding, and the potential benefits of adding microneedling.
The user is using oral finasteride and minoxidil for hair loss but reduced the dosage due to side effects like lightheadedness and weakness. They are also taking vitamins and natural DHT blockers.
Dutasteride 0.5 mg significantly reduces both scalp and hair follicle DHT, with a greater reduction in hair follicle DHT. The discussion questions which reduction is more important for androgenetic alopecia and diffuse thinning.
Alfatradiol is used by some for hair loss, often alongside treatments like finasteride, RU58841, and minoxidil, but its effectiveness is unclear. Some users report no significant improvement, while others note reduced sebum production but experience side effects like gallbladder pain.
A 25-year-old shared impressive hair regrowth results after 5 months using 5% topical minoxidil (Rogaine and Kirkland) and 1 mg oral finasteride (Propecia), with no shedding or side effects. The user applies minoxidil twice daily and finasteride once daily.
The conversation is about hair loss treatments, focusing on finasteride and minoxidil. Users suggest combining these with microneedling, but some recommend a hair transplant due to significant hair loss.
The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.
The user's progress after using dutasteride for hair loss treatment, and how minoxidil is also a helpful part of this process which can take up to one year to see full effects.
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
A user's experience of slowing hair loss while taking minoxidil and finasteride, and the various treatments suggested to help halt or reverse the process.
Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.
Ell-Cranell and Eucapil are discussed as hair loss treatments, with Ell-Cranell being a weak estrogen and DHT inhibitor that may reduce hair loss without systemic side effects. Alfatradiol is the active ingredient in these products.
The user shared progress pictures after 5 months of using topical minoxidil (1ml per day) and oral finasteride (1mg per day) for hair growth, with no side effects reported. The user also mentioned having a hair transplant in December and uses pH-neutral baby shampoo.
A 23-year-old male shared his 5.5-month progress using 5% topical minoxidil foam for hair regrowth, considering adding finasteride despite concerns about side effects. Users advised starting finasteride to maintain gains, with some suggesting topical options to minimize side effects.
People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.
A 22-year-old has been using finasteride 1mg daily and keto shampoo 1% weekly for hair loss with some progress but no significant regrowth yet. Users suggest waiting up to 18 months for results and possibly adding minoxidil or microneedling if needed.
The conversation discusses the potential benefits of adding Vitamin B6 (P-5-P) to topical hair loss treatments like RU58841, finasteride, or minoxidil. The user suggests that Vitamin B6 might enhance these treatments by naturally lowering scalp prolactin.
The user shared their 5-year hair regrowth journey using oral finasteride, oral dutasteride, topical and oral minoxidil, and a hair transplant. They experienced significant hair improvement without major side effects, although RU58841 was not effective for them.
The conversation is about finding a source for sterile dutasteride for mesotherapy to avoid side effects from oral 5AR blockers. The user is currently using microneedling and 0.01% topical dutasteride and plans to use transplants.
A man in his 40s treating his slow balding with a daily regimen of 2.5% spironolactone topical solution and Piroctone Olamine Shampoo. Despite initial hair shedding, he experienced no side effects and plans to continue the treatment for at least a year.
Discussion on hair loss treatments, focusing on pp405, with skepticism about its effectiveness and concerns about its association with the cosmetic industry. Users also mention treatments like Minoxidil and Finasteride.
A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.
The conversation discusses hair loss treatments, mentioning minoxidil, finasteride, RU58841, VDPHL, GT20029, and follicle cloning as potential solutions. It also reveals that the discussion about PP405 was an April Fool's joke.
The user has been using oral finasteride and topical minoxidil for years and recently started 2.5 mg oral minoxidil, with no significant regrowth observed yet. They are considering adding tretinoin cream to their regimen but are concerned about potential shedding.
The user tried various hair loss treatments including minoxidil, finasteride, hormone therapy, dutasteride, microneedling, and natural oils. They plan to continue their regimen and may consider surgical options if results are unsatisfactory.
The user has been using a treatment of 0.1% topical finasteride, 5% minoxidil, dermastamping, and vitamin D3 supplements for 85 days and is seeing good progress. Other users note the effectiveness of topical finasteride despite it being less potent.
The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.