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      community Clascoterone/ Breezula will it work

      in Research/Science 2 months ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

      community Diagnosed with a mild form of Alopecia

      in Treatment 6 years ago
      A user experienced rapid hair loss and was prescribed Desonide cream for mild Alopecia. They are seeking feedback on its effectiveness and potential side effects.

      community Quitting minox - going for alternatives

      in Minoxidil  4 upvotes 4 years ago
      The user stopped using minoxidil due to side effects and is trying alternatives like vitamin D supplementation, scalp massages, cold showers, oil treatments, zinc shampoo, and dermarolling. They report improved scalp health and some new hair growth, despite skepticism from others about the effectiveness of these methods.

      community How to get rid of dandruff once and for all?

      in Treatment  6 upvotes 3 years ago
      A 20-year-old male using Minoxidil and finasteride for 6 months and keto shampoo for 5 months saw initial improvement in dandruff, but the condition returned. He recently started using 3% salicylic acid shampoo and seeks advice for persistent dandruff, which is oily and localized to the left side of his scalp.

      community Reql minoxidil vs fake minoxidil (right)

      in Minoxidil  239 upvotes 1 year ago
      Counterfeit minoxidil is a concern, with users suggesting buying from reputable sources like Costco to ensure authenticity. A bleach test can help verify genuine minoxidil.

      community Can you actually buy Breezula?

      in Question  11 upvotes 7 years ago
      The conversation is about purchasing Breezula, a hair loss treatment. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community RU and Topical minoxidil together ?

      in Treatment  4 upvotes 2 years ago
      Using RU58841 and topical minoxidil together is fine and does not cancel out the benefits of each. Applying both treatments consecutively is acceptable.

      community Choose your topical antiandrogen and tell me why

      in Product  6 upvotes 1 year ago
      The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.

      community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

      in Minoxidil  71 upvotes 1 month ago
      Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

      community Is this Better Than Topical Minoxidil? Topical Diazoxide

      in Research/Science  6 upvotes 1 year ago
      Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Clascoterone powder already available?

      in Product  4 upvotes 2 months ago
      Clascoterone powder is now available, but it's expensive and not widely discussed due to past ineffective results at higher concentrations. Users are skeptical about its effectiveness and are seeking reliable sources.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community 30 M diffuse shining/bolding crown - stack

      in Treatment  2 upvotes 1 year ago
      A 30-year-old with diffuse thinning and a balding crown is using a treatment regimen of a 2-in-1 pill containing finasteride, minoxidil, and biotin, along with various supplements. After two weeks, no side effects have been experienced, and updates with pictures will be posted monthly.

      community Reducing Scalp Inflammation

      in Treatment  5 upvotes 5 years ago
      The conversation discusses treatments for scalp inflammation, suggesting options like scalp massage, changing shampoos, using aloe vera, Tgel, nizoral shampoo, topical cetirizine, and consulting a dermatologist. Finasteride was mentioned as helpful for reducing inflammation, but with side effects.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

      in Product  1 upvotes 8 months ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 7 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Question about topical part of treatment

      in Treatment  2 upvotes 2 years ago
      The user is using a combination of oral Dutasteride and Minoxidil, and a topical formula with Finasteride, Minoxidil, and Hydrocortisone, along with rosemary oil, coconut oil, ginseng, and a derma roller. They are also using LLLT therapy and are questioning the timing of the laser cap session in relation to the topical application.

      community Piroctone Olamine and Ketoconazole

      in Ketoconazole  7 upvotes 2 years ago
      Piroctone olamine and ketoconazole are both effective for reducing dandruff and hair shedding, with potential benefits for hair thickness and scalp health. Piroctone olamine may be as effective or better than ketoconazole in certain conditions, yet it is often overlooked.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

      community Min + Fin DIY with a cat, what can I use instead?

      in Product 7 months ago
      The user is concerned about the toxicity of a homemade topical solution of minoxidil and finasteride to their new kitten and is considering replacing minoxidil with stemoxydine. Other users suggest using oral treatments, keeping the solution away from the cat, and ensuring proper hygiene.

      community Selling a premixed KY19382 solution

      in Research/Science  7 upvotes 4 years ago
      The conversation discusses the sale of a premixed KY19382 solution for research purposes, highlighting previous unsuccessful group buys and the formulation process. Prices and purchasing options for KY19382 solutions and powder are provided.