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      community Pyrilutamide vs Ru58841 thoughts

      in Research/Science  8 upvotes 3 years ago
      The user has been using Pyrilutamide (Pyril) for hair loss for a month alongside finasteride/dutasteride since 2021 but hasn't seen results. They are considering switching to RU58841 due to its many success stories, despite being skeptical about the legitimacy and testing of Pyrilutamide.

      community RU and Topical minoxidil together ?

      in Treatment  4 upvotes 2 years ago
      Using RU58841 and topical minoxidil together is fine and does not cancel out the benefits of each. Applying both treatments consecutively is acceptable.

      community What makes breezula different than formula 82f?

      in Question  9 upvotes 6 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

      community Question about making a solution of RU58841

      in Treatment  1 upvotes 3 years ago
      The conversation is about making a solution of RU58841 using propanediol instead of propylene glycol due to skin irritation. The user seeks advice on whether this substitution is acceptable.

      community RU58841 2.5% in Minoxidil 5% 3ml twice a day - Less Hairfall "BUT"

      in Treatment  2 upvotes 2 years ago
      The user mixed RU58841 with Minoxidil for hair loss treatment and experienced reduced hair fall and thicker hair but stopped due to chest pain and muscle twitching. They plan to use a new routine without RU58841 or Finasteride due to side effects, including various topical treatments and peptides.

      community can you really buy RU58841 on amazon?

      in Product  2 upvotes 5 months ago
      RU58841 is discussed as a potential hair loss treatment, with questions about its availability on Amazon and daily application dosage. Minoxidil and finasteride are also mentioned as treatments.

      community Question about RU58841 in minoxidil

      in Minoxidil  5 upvotes 5 years ago
      The user is considering adding RU58841 to liquid minoxidil without propylene glycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.

      community Anyone ever use amazons RU58841?

      in Product  21 upvotes 2 years ago
      The conversation warns against buying RU58841 from Amazon due to concerns about product authenticity and recommends purchasing from trusted sources like Minoxidilmax and Anageninc.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  243 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community Cure/better treatment options in the future

      in Chat  11 upvotes 1 year ago
      The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.

      community GT20029 Will Replace Finasteride For Hair Loss

      in Research/Science  50 upvotes 1 month ago
      GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.
      Is Oral Minoxidil Chewables not as effective?

      community Is Oral Minoxidil Chewables not as effective?

      in General  31 upvotes 1 year ago
      Hims chewable oral minoxidil may be less effective due to its form and dosage of 2.5 mg. The effectiveness is questioned because the source criticizing it sells a competing product.

      community Is there any way to get Ru58841 in India?

      in Treatment  8 upvotes 4 months ago
      RU58841 is not FDA approved, and users are discussing its availability and legitimacy in India, with some mentioning brands like Vantanex and Capomil. One user warns about the risk of gyno from RU58841, advising to stop use at the first sign of sensitivity.

      community Getting bloods done whilst on finasteride

      in General  98 upvotes 1 year ago
      Finasteride can affect hormone levels within two weeks, and a break of several weeks is recommended for baseline results. Monitoring E2 and testosterone is suggested to assess the risk of gynecomastia.

      community Thinking about signing up for the setipiprant clinical trials

       4 upvotes 9 years ago
      The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 6 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 1 year ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community HMI-115 when will it be available

      in Research/Science  15 upvotes 3 years ago
      The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 4 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community Will PP405 render Minox and Fin obsolete?

      in Research/Science  26 upvotes 1 year ago
      PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.

      community Using a 2-deoxy-d-ribose gel. My experience 2 weeks in.

      in Treatment  38 upvotes 11 months ago
      The user switched from minoxidil to a homemade 2-deoxy-d-ribose gel and noticed no hair fall after two weeks, despite stopping minoxidil. The gel includes water, 2-deoxy-d-ribose, vegetable glycerine, 2-phenoxyethanol, sodium alginate, and rosemary oil, and the user reports healthier-feeling hair.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 6 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.